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Hypoxia-induced miR-21-5p promotes autophagy by downregulating CDC25A in endometriosis.

Endometriosis is a common gynecological disorder affecting women of reproductive age, often leading to chronic pain, reduced quality of life, and infertility. It is characterized by ectopic endometrial growth within …

Published: March 30, 2026, midnight
Charting the nerve-immune axis in endometriosis.

Endometriosis is increasingly recognized as a systemic disorder involving complex interactions between nerves and immune cells, driving chronic pain and inflammation beyond the initial theories. Recent breakthroughs highlight aberrant sensory …

Published: March 26, 2026, midnight
Serum neurofilament light chain in fibromyalgia: comparative evidence of neuronal injury across chronic pain conditions.

Evidence increasingly shows small nerve fibre pathology in subsets of people with fibromyalgia through skin biopsy, corneal confocal microscopy, and microneurography. However, blood-based biomarkers of ongoing neuronal damage, particularly neurofilament …

Published: March 24, 2026, midnight
Medical Treatment for Endometriosis: One Size Does Not Fit All.

Endometriosis is associated with nociceptive pain, as well as peripheral and central sensitization. Evidence-based treatment suggestions for controlling endometriosis should be based on the convergence of the best scientific evidence, …

Published: March 21, 2026, midnight
Effects of 8-weeks acupuncture on eyes-closed resting state natural EEG frequency components in endometriosis: AcuENDO trial sub-study.

The aim of this study was to examine changes in resting electroencephalography (EEG) activity associated with an 8-week acupuncture intervention for women with endometriosis and chronic pelvic pain.

Published: March 13, 2026, midnight
Improving health-related quality of life in patients with endometriosis-related chronic pain: the COGENS trial.

Published: March 12, 2026, midnight
Beyond nociception: rethinking pain in ovarian endometriosis a pilot study.

Endometriosis affects 1 in 10 women, is the most common cause of chronic pelvic pain, classically known for its nociceptive pain mechanisms. Medical therapies have limited efficacy, prevent pregnancy, and …

Published: March 11, 2026, midnight
Standardizing medical pain management for the endometriosis patient: A Dutch modified eDelphi procedure.

to develop a step-by-step guideline to the medical management of pain in women with endometriosis from a national modified eDELPHI process in the Netherlands.

Published: Feb. 26, 2026, midnight
Pelvic Congestion Syndrome: The Gynecological Perspective.

Background/Objectives: Chronic pelvic pain (CPP) is defined as pelvic pain lasting longer than six months and is a common yet often overlooked condition, affecting over 40% of women worldwide and …

Published: Feb. 22, 2026, midnight
Central sensitization in women with endometriosis: a cross-sectional study.

Pain is the primary symptom of endometriosis and may progress into a chronic, acyclic condition driven by neuroinflammatory mechanisms, leading to neuropathic and ultimately nociplastic pain. Central sensitization, a form …

Published: Feb. 17, 2026, midnight
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