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Endobiota-Estrobolome Profiles in Reproductive-Aged Women With Ovarian Endometriosis.

This case-control study investigated whether ovarian endometriosis is associated with altered estrogen metabolism and gut or urogenital microbiota by analyzing enzyme activity, bacterial composition, and variations of estrogen metabolites in …

Published: May 12, 2026, midnight
The estrobolome and its emerging role in endometriosis pathogenesis: no guts, no story?

Published: March 28, 2026, midnight
The role of gut microbiota in modulating estrogen in the inflammatory milieu of endometriosis: A molecular and pathophysiological perspective.

Endometriosis is a prevalent estrogen-dependent chronic inflammatory condition that affects millions of women of reproductive age worldwide. It is characterized by the growth of endometrial tissue outside the uterine cavity, …

Published: Feb. 24, 2026, midnight
The role of probiotics in the treatment of endometriosis (ProMetrioS): a randomized double-blinded placebo-controlled cross-over trial.

ProMetrioS is a randomized, blinded, placebo-controlled cross-over trial investigating the effect of a specific multispecies probiotic in patients with endometriosis. The aim of this clinical trial is to determine whether …

Published: Feb. 20, 2026, midnight
A Dive into the Invisible: The Vaginal and Endometrial Microbiota in Gynecologic and Obstetric Disorders: A Narrative Review.

The human microbiota is increasingly recognized as a key component of women's reproductive health. This narrative review examines the vaginal, endometrial, and gut microbiota and their roles in the pathogenesis …

Published: Feb. 17, 2026, midnight
ESTROBOLOME: IS THERE A MISSING LINK?

Estrogens play an important role throughout a woman's life; therefore, disrupting their physiological production will alter hormonal balance with consequences for estrogen-related conditions, such as endometriosis and adenomyosis. The gut …

Published: Feb. 16, 2026, midnight
Gut Microbiota Alterations and Reproductive Tract Dysbiosis in Endometriosis: A Systematic Review.

Background and Objectives: Endometriosis is a chronic, estrogen-dependent inflammatory disease with multifactorial pathogenesis. Increasing evidence suggests that alterations in the gut and reproductive tract microbiota may contribute to disease development, …

Published: Feb. 10, 2026, midnight
Gut Microbiota Alterations in Endometriosis: An Observational Study in a Spanish Female Cohort.

Identifying potential gut biomarkers linked to endometriosis for diagnosis and treatment.

Published: Dec. 18, 2025, midnight
Could the estrobolome have a role in endometriosis pathogenesis and infertility? A systematic review.

Endometriosis is a chronic, estrogen-dependent condition affecting 10% of reproductive-aged women, often associated with infertility and chronic pelvic pain. Recent evidence suggests that gut microbiota dysbiosis and alterations in the …

Published: Dec. 18, 2025, midnight
Unraveling the Contribution of Estrobolome Alterations to Endometriosis Pathogenesis.

Endometriosis (EMS) is a long-term inflammatory disease. It represents one of the most prevalent gynecological conditions, impacting an estimated 5% of reproductive women. Therefore, endometriosis contributes to substantial worldwide health …

Published: July 1, 2025, midnight
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