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Spontaneous conception and successful live birth during hormone replacement therapy in a patient with iatrogenic premature ovarian insufficiency: a case report.

Premature ovarian insufficiency (POI) is defined as loss of ovarian function before the age of 40 years. It has a profound impact on patients' quality of life, particularly due to …

Published: Aug. 25, 2026, midnight
Postmenopausal endometriosis: current evidence and clinical challenges in diagnosis and treatment.

Endometriosis was once thought to affect only reproductive-aged women. However, 2-5% of postmenopausal individuals remain affected. Guidance for this group is limited. This review outlines an updated approach to postmenopausal …

Published: Aug. 24, 2026, midnight
Clinical Appraisal of "Micronized Vaginal Progesterone Dose and Serum Progesterone Thresholds Determine Reproductive Outcomes in Frozen-Thawed Embryo Transfer With Hormone Replacement Therapy".

This paper critically evaluates Sekiguchi et al.'s study of vaginal progesterone dose, serum progesterone thresholds, and reproductive outcomes in hormone replacement therapy frozen embryo transfer (HRT-FET) cycles. The study conflates …

Published: Aug. 19, 2026, midnight
Natural versus artificial cycle for endometrial preparation in ovulatory women undergoing frozen-thawed embryo transfer: a randomised controlled trial.

Does a natural cycle result in higher clinical pregnancy rates (CPR) with foetal heartbeat compared to an artificial cycle for frozen-thawed embryo transfer (FET) preparation in ovulatory women?

Published: June 19, 2026, midnight
Menopausal hormone use after hysterectomy in endometriosis: a Finnish register-based study.

This study aimed to examine the frequency and type of menopausal hormone therapy (MHT) use after hysterectomy among women with surgically diagnosed endometriosis.

Published: April 1, 2026, midnight
Associations of surgical menopause and hormone replacement therapy with meningioma development.

Bilateral salpingo-oophorectomy (BSO) and hormone replacement therapy (HRT) exert opposing effects on systemic sex hormone exposure. Although HRT is frequently prescribed following BSO to mitigate surgical menopause, their combined impact …

Published: March 12, 2026, midnight
Navigating menopausal health in Oman (Marie Oman WP2a).

Published: March 5, 2026, midnight
Effect of Astragalus sinicus Ethanol Extract on Menopausal Symptoms in an Ovariectomized (OVX) Mouse Model.

As the aging population grows, the proportion of postmenopausal women is also increasing. Menopause can cause various symptoms and reduce quality of life. Hormone replacement therapy (HRT) is a common …

Published: Jan. 23, 2026, midnight
Long-Term Burden of Adolescent-Onset Endometriosis: A Case Report Highlighting Recurrent Disease and Fertility-Preserving Dilemmas.

Adolescent-onset endometriosis is increasingly recognized as a distinct clinical challenge. It often requires years to achieve a diagnosis, leading to prolonged physical and psychological distress and significantly impairing quality of …

Published: Nov. 20, 2025, midnight
Understanding Peritoneal Fluid Estrogen and Progesterone Concentrations Permits Individualization of Medical Treatment of Endometriosis-Associated Pain with Lower Doses, Especially in Adolescents Not Requiring Contraception.

Objectives: The aim of this study was to review the importance of peritoneal fluid steroid hormone concentrations to understand the mechanism of hormonal medical treatment of endometriosis-associated pain. Design: The …

Published: Oct. 12, 2025, midnight
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