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Biomaterials for Reproductive Restoration: Translating Engineering Innovations.

Advances in cancer therapy, delayed parenthood, and an increasing number of reproductive disorders have intensified the need for the effective preservation of fertility. However, current clinical strategies such as ovarian …

Published: Jan. 22, 2026, midnight
Development of medical freezing measures in women during the last decade from 2014 to 2023: registry data of the tri-national network FertiPROTEKT.

To what extent have fertility preservation interventions evolved between 2014 and 2023, and what factors have influenced changes in their utilization and prevalence?

Published: Jan. 13, 2026, midnight
Noninvasive BCL6 Preoperative Screening and Anatomic Patterns of Endometriosis in Patients with Unexplained Infertility.

Background/Objectives: Endometriosis is a chronic, inflammatory, estrogen-dependent disease that has historically been underdiagnosed, especially in patients with unexplained infertility. On average, diagnosis is delayed by 11 years, underscoring the need …

Published: Jan. 4, 2026, midnight
Ethanol sclerotherapy for endometriomas: a fertility-preserving alternative.

Endometriomas are a common manifestation of endometriosis in women of reproductive age and pose a clinical challenge due to their association with pain, infertility, and compromised ovarian reserve. Surgical removal …

Published: Dec. 4, 2025, midnight
Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway.

Endometriosis‑associated infertility is considered to be linked to cellular senescence. The present study assessed whether rapamycin, a senescence inhibitor, ameliorates endometriosis‑associated infertility by upregulating peroxisome proliferator‑activated receptor α (PPARα) and …

Published: Oct. 31, 2025, midnight
Identification of Adeno-Associate Virus (AAV) Serotype for Endometriosis Therapy and Effect of AAV-Mediated RNAi Delivery on Gene Expression and Cell Proliferation in In Vitro Endometrial Cell Culture.

Endometriosis is a chronic estrogen-dependent condition with limited treatment options, often requiring surgery and long-term hormonal therapy that may impair ovarian function. Despite advancements in gene therapy for other diseases, …

Published: Sept. 13, 2025, midnight
Fertility preservation in endometriosis: evaluating surgical risks and emerging preservation approaches.

Endometriosis poses significant challenges for women of reproductive age, particularly due to its impact on ovarian reserve and fertility. In addition to endometriosis-associated infertility contributing to diminished ovarian reserve by …

Published: Aug. 16, 2025, midnight
Extended Ovarian Transport for Centralized Tissue Cryobanking: Impact on Primordial Follicle Integrity.

To evaluate the impact of ovarian tissue transportation on human primordial follicle integrity prior to cortical tissue cryopreservation.

Published: Aug. 7, 2025, midnight
Iron deposition in ovarian endometrioma evaluated by magnetic resonance imaging R2* non-invasively.

Is surgery effective in decreasing iron deposition in the ovarian tissue surrounding an ovarian endometrioma?

Published: April 24, 2025, midnight
Creation of a rat model of ovarian endometriosis: a novel and easy approach to simulating chocolate cysts.

Ovarian endometriosis(OEM) is the most common type of endometriosis, but there is still a lack of simple and easy-to-promote animal models. Therefore, it is necessary to establish a feasible animal …

Published: April 9, 2025, midnight
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