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The endometriosis-adenomyosis spectrum: shared pathophysiology and microenvironment-driven disease divergence.

Endometriosis and adenomyosis are common gynecologic disorders associated with dysmenorrhea, chronic pelvic pain, and infertility. Although they share several molecular features, the mechanisms by which endometrium-derived tissues develop distinct pathological …

Published: July 8, 2026, midnight
Functional Analysis of the Histidine N-Methyltransferase SETD3 in Endometriosis.

Endometriosis is a disease associated with pain symptoms and reduced fertility, characterized by the presence of endometrial tissue outside the uterus. SETD3 is an actin-specific histidine N-methyltransferase that regulates actin …

Published: July 7, 2026, midnight
Impaired PIEZO1 function drives uterine hypercontractility in adenomyosis-associated dysmenorrhea.

Does PIEZO1 play any role in adenomyosis-associated dysmenorrhea?

Published: Feb. 17, 2026, midnight
Looking at endometriosis-diagnosis and disease mechanisms through a mechanical lens.

Endometriosis is a chronic gynecological disorder marked by the growth of endometrial-like tissue outside the uterus, often resulting in pain and infertility and affecting overall quality of life. Despite its …

Published: Feb. 5, 2026, midnight
Endometrial Stromal Cells from Endometriosis Patients Reflect Lesion-Type-Specific Heterogeneity.

Endometriosis, a disease affecting about one out of ten women, is characterized by the growth of endometrial-like tissue outside the uterine cavity. There is significant disease heterogeneity, but the pathophysiological …

Published: Nov. 28, 2025, midnight
Decoding uterine contractility: from physiology to pathology, through emerging technologies.

Uterine contractility has emerged as a potential key element in the orchestration of female reproductive functions, with specific motility patterns seemingly aligning with hormonal fluctuations throughout the menstrual cycle. These …

Published: Oct. 30, 2025, midnight
Effects of Endometriosis, Fibroids, and Other Pathological Conditions on Muscular Contractions in the Human Fallopian Tube.

Ectopic pregnancy (EP) and tubal endometriosis (TEM) directly affect the fallopian tube structure and function, while ovarian cysts (OC) and uterine fibroids (UF) may indirectly influence tubal physiology. These conditions …

Published: Oct. 2, 2025, midnight
Cine-MRI for Quantifying Uterine Peristalsis: A Systematic Review and Meta-Analysis.

Background: Uterine contractility, also known as uterine peristalsis (UP), is a critical determinant of fertility, affecting sperm transport and embryo implantation. Increased uterine peristaltic activity has been associated with reduced …

Published: Feb. 6, 2025, midnight
The effect of lysophosphatidic acid on myometrial contractility and the mRNA transcription of its receptors in the myometrium at different stages of endometrosis in mares.

Endometrosis (chronic degenerative endometritis) results in morphological changes in the equine endometrium and impairs its secretory function. However, the effect of this condition on the myometrium remains unclear. Lysophosphatidic acid …

Published: Dec. 19, 2024, midnight
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