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Research Progress of Histone Deacetylase and Its Inhibitors in Endometriosis.

Endometriosis is a complex chronic inflammatory disease with an unclear etiology and limited treatment options, severely affecting the reproductive health and quality of life of many women. Histone deacetylases (HDACs), …

Published: Sept. 9, 2026, midnight
Exosomal miR-22-3p targets p53 to regulate endometrial epithelial cell function in the pathogenesis of endometriosis.

Endometriosis (EMs) is a widespread gynecological disease, affecting approximately 6-10% of females of child-bearing age. Despite its significant influence on women's health, the specific pathophysiology remains unclear. The enrichment of …

Published: Sept. 4, 2026, midnight
Shared genetic architecture and cellular convergence between female reproductive disorders and pulmonary function: a genome-wide cross-trait analysis.

Female reproductive disorders (FRDs), including polycystic ovary syndrome, endometriosis, uterine leiomyomata, and infertility, have been epidemiologically associated with impaired pulmonary function. However, it remains unclear whether this cross-organ link reflects …

Published: Sept. 1, 2026, midnight
Research Progress of Autophagy and Ferroptosis in Endometriosis.

Endometriosis (EMs) is a common and refractory disease in clinical practice.It has the pathological characteristics of adhesion and invasion,while the pathogenesis remains unclear.In recent years,studies have found that autophagy and …

Published: Aug. 29, 2026, midnight
Evidence-based recommendations for advancing the chronic pelvic pain syndrome management by the paradigm change from reactive symptom suppression to proactive 3PM-guided patient-centered care.

Chronic pelvic pain syndrome (CPPS) encompasses a heterogeneous group of debilitating conditions including interstitial cystitis/bladder pain syndrome (IC/BPS), chronic abacterial prostatitis, endometriosis, and pelvic congestion syndrome, among others. Despite advances …

Published: Aug. 28, 2026, midnight
The role of SYNE1/2 variants as a potential predisposition factor for the onset of endometriosis.

Endometriosis (EM) is a chronic, inflammatory gynaecological disorder defined by the presence of endometrial-like tissue outside the uterine cavity, most frequently affecting the ovaries, peritoneum, and uterosacral ligaments. Despite its …

Published: Aug. 25, 2026, midnight
[The Laterality of Endometriosis].

Endometriosis, affecting 10-15% of women of reproductive age, is more commonly found on the left side of the pelvis. This laterality phenomenon's etiology remains obscure. We reviewed the existing literature …

Published: Aug. 7, 2026, midnight
Gut commensal Olsenella profusa promotes endometriosis via lysophosphatidylcholine metabolite.

Endometriosis (EM) is an intractable gynecological condition with uncertain etiology. Gut microbiota have been increasingly implicated in EM, yet the underlying mechanisms remain unclear. Here, we identify a gut microbe-metabolite-uterus …

Published: Aug. 5, 2026, midnight
Microplastics and female infertility: reproductive toxicity and underlying mechanisms.

In modern society, the progression of ovarian aging in women has accelerated, and the incidence of infertility has increased markedly with a distinct younger-onset trend. Exploring the etiology and pathogenesis …

Published: Aug. 3, 2026, midnight
Dietary and Environmental Exposure to Toxic Elements in Endometriosis: A Missing Piece of the Etiological Puzzle?

Background/Objectives: Endometriosis is a chronic estrogen-dependent disease with a complex and incompletely understood etiology. Environmental exposure to toxic elements, including cadmium, lead, mercury, and arsenic, may contribute to its development …

Published: Aug. 2, 2026, midnight
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