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The Microbiome-Gut-Gonad Axis: How Microbial Metabolites Orchestrate Reproductive Physiology, Pathology, and Therapy.

The human microbiome, a dynamic endocrine organ, exerts profound systemic influence through the production of bioactive metabolites. While the microbiome-gut-brain axis is well-established, the direct conduit between the gut microbiota …

Published: July 4, 2026, midnight
Analysis of Drug Clinical Trials in Obstetrics and Gynecology: A Five-Year Retrospective Study from a Public Tertiary Specialty Hospital in China.

Women remain underrepresented in clinical drug development despite their unique biological characteristics and growing disease burden. In China, this disparity is particularly concerning given the rising incidence of gynecologic conditions …

Published: June 30, 2026, midnight
Design and implementation of interventions to improve sexual health of women with endometriosis: A mixed-methods study protocol with an interventional design.

Endometriosis has potential negative effects on the fertility, mental, and sexual health of women. Since the conducted studies have not comprehensively addressed the needs and strategies to improve sexual health, …

Published: June 2, 2026, midnight
Patient characteristics and lifestyle determinants of quality of life among women with endometriosis: a systematic review.

Endometriosis is a chronic inflammatory disease presenting with debilitating symptoms strongly impacting patients' quality of life (QoL). Assessing QoL is crucial for understanding the full patient experience beyond clinical symptoms. …

Published: May 20, 2026, midnight
Percutaneous image-guided cryoablation of umbilical endometriosis: safety, feasibility, clinical, and imaging outcomes.

To evaluate the safety, feasibility and imaging outcomes of percutaneous image-guided cryoablation as a minimally invasive treatment for umbilical endometriosis (UE).

Published: May 11, 2026, midnight
[Investigation of pharmacological regimens combined with focused ultrasound ablation surgery for alleviating dysmenorrhea in extrinsic adenomyosis].

Objective: To investigate optimal long-term medication regimens combined with focused ultrasound ablation surgery (FUAS) for alleviating dysmenorrhea in patients with extrinsic adenomyosis. Methods: A retrospective research enrolled patients with extrinsic …

Published: April 29, 2026, midnight
The efficacy of ultrasound-guided treatment of ovarian endometriosis cysts: A meta-analysis.

The purpose of this meta-analysis was to systematically assess the efficacy of ultrasound-guided therapy of ovarian endometriosis cyst (OEC). Several databases were searched to gather published studies on the efficacy …

Published: April 15, 2026, midnight
Contemporary Diagnostic and Therapeutic Approaches in Endometriosis: A Systematic Review.

Endometriosis is a chronic inflammatory disorder characterized by pelvic pain, infertility, and reduced quality of life, and is frequently associated with prolonged diagnostic delay and variable treatment response. Although advances …

Published: April 3, 2026, midnight
Adenomyosis Pathophysiology, Diagnostic Advances, and Therapeutic Options.

Adenomyosis is a heterogeneous, nonmalignant uterine disorder characterized by ectopic endometrium within the myometrium, leading to abnormal uterine bleeding, dysmenorrhea, chronic pelvic pain, and subfertility. Once considered a disease of …

Published: April 2, 2026, midnight
From lipid profiles to disease onset: Triglycerides as predictive biomarkers in endometriosis.

Dyslipidaemia is related to endometriosis, but it is not known which lipid component is most relevant, and whether the observed correlation reflects the causal relationship. The relationship between triglycerides (TG) …

Published: March 7, 2026, midnight
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