Dysmenorrhea is the most common gynaecological condition in women of reproductive age. Approximately 90% of cases are primary dysmenorrhea (PDM) which is not associated with underlying pathology. Dysmenorrhea can have …
Introduction. Endometriosis affects 10-20% of reproductive-age women. Emerging evidence links the gut microbiota to endometriosis pathogenesis, but observational studies are limited by confounding, reverse causation and uncertainty about whether reported …
The potential bidirectional causal relationship between endometriosis and serum 25-hydroxyvitamin D has been previously investigated. Nevertheless, the results could be impacted by confounding factors and reverse causality because of the …
Preimplantation genetic testing for aneuploidy (PGT-A) is widely used to screen for embryo aneuploidy, enabling the selection and transfer of genetically normal embryos. Despite its potential to improve clinical outcomes, …
The study aimed to investigate familial transmission patterns in women with endometriosis by generating a customized single-nucleotide polymorphism (SNP) array.
Ovarian endometriosis (OEM) is characterised by ectopic endometrial tissue growth within the ovary. In these ectopic lesions, the ectopic epithelium plays a crucial role in OEM progression and has been …
This study aims to investigate the effect of endometriosis (EMs) on fertility and to assess the causal relationship between EMs and fertility using two-sample Mendelian randomization (MR). We conducted an …
Multi-omics data are instrumental in obtaining a comprehensive picture of complex biological systems. This is particularly useful for women's health conditions such as endometriosis, which has been historically understudied despite …
Identification of appropriate biomarkers is of great clinical significance for early diagnosis of endometriosis (EMs). This study aimed to comprehensively analyze the association between EMs and blood and urine biomarkers …
Systemic lupus erythematosus (SLE) is a clinically heterogeneous autoimmune disease with multifactorial pathogenesis. Although polygenic risk scores (PRSs) have been developed to enable early prediction, their accuracy remains limited. To …