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CSF3R signalling beyond granulopoiesis: new paradigms in female reproductive biology.

The Colony-Stimulating Factor 3 Receptor (CSF3R), the receptor for granulocyte colony-stimulating factor (G-CSF), has expanded from a hematopoietic regulator to a multifunctional signalling molecule with significant relevance in gynaecological biology. …

Published: April 7, 2026, midnight
Genetically-predicted placental gene expression links to uterine fibroids and endometriosis.

Mother-to-child disease transmission begins in utero, with the placenta playing a critical role in pregnancy and offspring health. Uterine leiomyomata (fibroids, UFs) and endometriosis (ENDO) are common gynecologic diseases that …

Published: April 1, 2026, midnight
Clinical Characteristics and Management of Ovarian Endometrioma Complicated by Infertility Treatment-Induced Tubo-Ovarian Abscess: A Retrospective Study.

To evaluate the incidence of tubo-ovarian abscess (TOA) in patients with ovarian endometrioma (OE) undergoing infertility treatment and to describe treatment approaches and clinical outcomes, including transvaginal ultrasound-guided drainage.

Published: March 31, 2026, midnight
YWHAZ Loss Is Associated With Endometrial Dysfunction in Proliferative Phase Endometriosis.

Endometriosis is an estrogen-dependent inflammatory disorder frequently associated with infertility and characterized by progesterone resistance and impaired endometrial receptivity. While ectopic lesions define the disease, accumulating evidence indicates that molecular …

Published: March 26, 2026, midnight
Endo-SOFT: study protocol for a national multicentre randomised controlled trial - first-line surgery versus first-line assisted reproductive technologies in patients with advanced endometriosis.

Endometriosis is a chronic, inflammatory and oestrogen-dependent disease frequently causing infertility. Assisted reproductive technologies (ART) are often required to achieve pregnancy, especially in women with advanced endometriosis. To date, there …

Published: March 25, 2026, midnight
Safety and Reproductive Outcomes of Minimally Invasive Nerve-Sparing Surgery for Deep Endometriosis in Infertile Women: A One-Year Follow-Up Study.

Background/Objectives: Deep endometriosis is a chronic inflammatory disease that significantly affects fertility. The objective was to evaluate the magnitude of the effect of minimally invasive nerve-sparing complete excision of endometriosis …

Published: March 17, 2026, midnight
The impact of adenomyosis localization in myometrium on fertility and pregnancy outcomes: a narrative systematic review of the literature.

Adenomyosis can be categorized using various systems based on its extent, location, and severity. Depending on its location within the endometrium adenomyosis can be classified as intrinsic (inner myometrium) or …

Published: March 16, 2026, midnight
Fertility outcomes after conservative versus radical surgery in moderate to severe endometriosis with deep endometriosis.

Does laparoscopic radical excision of deep endometriosis (DE) and enucleation of endometrioma improve fertility outcomes and reduce recurrence rates in patients with moderate to severe endometriosis?

Published: March 13, 2026, midnight
Disruption of primary ciliary prostaglandin E2 signaling by transforming growth factor-β1 impairs endometrial receptivity.

Infertility affects one in six individuals worldwide despite the advancement of assisted reproductive technologies. Successful embryo implantation is the first step of pregnancy, which relies on the establishment of a …

Published: March 11, 2026, midnight
HIGH VERSUS STANDARD DOSE FOLIC ACID SUPPLEMENTATION FOR MISCARRIAGE PREVENTION: SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS.

To assess whether high-dose folic acid supplementation (4-5 mg/day), initiated before conception, reduces the risk of miscarriage and improves pregnancy rates compared to standard-dose supplementation (0.4 mg/day).

Published: March 11, 2026, midnight
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