Treatment for women with endometriosis is only partially or temporarily effective. Moreover, medical hormonal treatment is associated with debilitating side effects and interferes with fertility, while surgery has a relatively …
Menstrual health symptoms, including painful periods, heavy bleeding, and premenstrual syndrome (PMS), are prevalent in midlife women and may be influenced by lifestyle factors. Identifying modifiable health behaviours associated with …
Adenomyosis and endometriosis are two sister diseases that cause menstrual pain and other symptoms. We have previously reported that patients with these conditions have a less active "calm-and-rest" system and …
Endometriosis-associated pelvic pain represents a prototypical failure of systemic therapy for a locally organized, neuroinflammatory disease. Persistent pain arises from the convergence of estrogen-driven lesion survival, chronic inflammation, fibrosis, and …
Endometriosis is a chronic inflammatory disease presenting with debilitating symptoms strongly impacting patients' quality of life (QoL). Assessing QoL is crucial for understanding the full patient experience beyond clinical symptoms. …
Endometriosis is a chronic pain condition that affects >190 million people worldwide. It is recommended in clinical guidelines to remove the most common type of endometriosis, 'superficial peritoneal endometriosis' (SPE), …
Endometriosis is a common, inflammatory condition impacting 200 million women and those assigned female at birth, where 25-40% experience infertility. Ovarian endometriosis is known to decrease anti-Mullerian hormone (AMH) levels …
Endometriosis is a chronic, estrogen-dependent disorder defined by ectopic endometrial-like tissue growth, persistent inflammation, and aberrant innervation. Emerging evidence indicates that disease progression and symptom severity are driven by a …
This study aims to propose a novel, reproducible transvaginal ultrasound (TVUS) measurement-anterior-posterior wall thickness of the uterine isthmus ratio (APTUIR)-and to construct a nomogram model integrating this parameter with other …
To develop a predictive risk score for superficial peritoneal endometriosis (SPE) in patients with negative examination and imaging based on symptoms and quality of life measures DESIGN: Multicenter nested case-control …