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A Scoping Systematic Review of Cannabis Use in Endometriosis.

Endometriosis, affecting 6%-10% of reproductive-age women, causes chronic pelvic pain, dysmenorrhea, and infertility. Current treatments have limitations and consequently there is rising interest in effects of cannabis on pain and …

Published: Dec. 9, 2025, midnight
Microvascular hypoxia and inflammation in chronic pain syndromes.

In this opinion, we propose that compromised microvascular perfusion and inflammation are fundamental drivers of chronic pain syndromes, with many of these conditions sharing a common etiology involving suboptimal blood …

Published: Dec. 8, 2025, midnight
Infertility management in patients with bowel endometriosis: the current landscape and the promise of randomised trials: a narrative review.

The management of infertility in women with bowel endometriosis remains a significant clinical challenge. The two primary therapeutic approaches include first-line medically assisted reproduction (MAR) and primary bowel surgery, with …

Published: Dec. 3, 2025, midnight
High inhibition ratio and transformation index of 2 mg dienogest: further evidence for its use in endometriosis treatment.

Endometriosis is a common, chronic disease with a high burden for women, characterised by the implantation of endometrial cells outside the uterus. Many different treatments have been proposed for this …

Published: Dec. 2, 2025, midnight
Natural bioactive compounds and herbal medicines targeting common signaling pathways in endometriosis: mechanisms and therapeutic implications.

For a very long time, herbal treatments have served as remedies for various humans and animals. Natural compounds typically have multiple pharmacological actions because they interact with various biological targets. …

Published: Dec. 2, 2025, midnight
Patients' knowledge, attitudes, and practices concerning endometriosis and its long-term management.

Endometriosis, affecting 10-15% of women, causes pain and infertility. Current treatments have limitations. This study aimed to investigate patients' knowledge, attitude, and practice (KAP) concerning endometriosis and its long-term management.

Published: Nov. 28, 2025, midnight
The Financial Toxicity of Endometriosis: Unseen Costs and Policy Gaps.

Endometriosis affects 1 in 10 Canadians, yet its financial toxicity remains poorly understood. While universal healthcare covers physician and hospital services, patients face substantial out-of-pocket costs for medications, complementary therapies, …

Published: Nov. 28, 2025, midnight
Personalized Vaginal Drug Delivery through 3D Printing: Techniques, Challenges, and Future Perspectives.

Vaginal disorders in reproductive‑age women, including bacterial vaginosis (affecting 23-29%), endometriosis, etc., are increasing alarmingly day by day worldwide. Vaginal drug delivery (VDD) has garnered notable attention in the pharmaceutical …

Published: Nov. 26, 2025, midnight
Interventions for endometriosis-related pain and infertility: a protocol for systematic review and network meta-analysis.

Endometriosis, a chronic oestrogen-dependent disorder, presents significant clinical challenges including pelvic pain, dysmenorrhoea, dyspareunia and infertility. While numerous interventions exist, evidence guiding the choice among surgical, hormonal and non-hormonal therapies …

Published: Nov. 13, 2025, midnight
Evaluating the Effect of Exosome-Encapsulated miR-4289 on Menstrual Blood-Derived Mesenchymal Stem Cells from Endometriosis Patients.

Endometriosis is a benign yet chronic gynecological disorder characterized by dysregulation of processes such as inflammation, angiogenesis, migration, apoptosis, and proliferation. Menstrual blood-derived endometrial stem cells play a crucial role …

Published: Nov. 11, 2025, midnight
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