Relugolix is an oral, non-peptide gonadotropin-releasing hormone receptor antagonist administered as once-daily combination therapy (relugolix-CT; 40 mg relugolix, 1 mg estradiol, 0.5 mg norethindrone acetate) to reduce endometriosis symptoms while …
Endometriosis may contribute to the onset of pelvic floor dysfunction (PFD) but data on urologic and bowel symptoms in endometriosis patients are scant. The aim of this study is to …
To compare the clinical effectiveness of combined oral contraceptive pills (levonorgestrel-containing COC) and dienogest in the management of endometriosis-associated chronic pelvic pain and related symptoms.
Single-cell RNA sequencing is a state-of-the-art approach to decipher the heterogeneity of RNA transcripts in individual cells and identify different cell types in tissues and organs. Its aim is to …
This study aimed to evaluate the impact of an 8 weeks functional strength training program on physical performance, pain perception, and quality of life in women with endometriosis.
Endometriosis is a chronic estrogen-dependent disorder characterised by the growth of endometrial-like tissues outside the uterus. Recent data suggest a potential role for endometrial stem/progenitor cells in the development of …
Exercise may be an effective tool to improve symptoms and quality of life in those with endometriosis. However, the optimal dose to elicit such changes is unknown. This study will …
Assisted reproductive treatment for women with endometriosis and diminished ovarian reserve (DOR) is challenging, and the optimal controlled ovarian stimulation (COS) protocol for this population remains uncertain. This study compared …
Cardiovascular disease (CVD) remains the leading cause of mortality globally. Emerging evidence indicates that cardiovascular risk in women is frequently underestimated, underscoring the importance of recognizing sex-specific contributors. Endometriosis is …
Daughters of women with endometriosis are known to be at increased risk of developing this disease. Using a mouse model, we demonstrate uterine dysfunction reminiscent of endometriosis patients can also …