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HEXACHLOROBENZENE AND CHLORPYRIFOS, ENVIRONMENTAL POLLUTANTS THAT DISRUPT THE ENDOCRINE SYSTEM, PROMOTE ANGIOGENESIS ASSOCIATED WITH ENDOMETRIOSIS.

Endometriosis defined by the growth of endometrial tissues outside the uterus, affects women of reproductive age. A critical process in endometriosis progression, angiogenesis involves endothelial cell migration, proliferation and tube …

Published: June 5, 2026, midnight
SGLT2 Inhibition as a Novel Therapeutic Strategy in Rheumatic Heart Disease.

Rheumatic heart disease (RHD) remains a major cause of cardiovascular morbidity and premature mortality among children and young adults, particularly in low- and middle-income countries. Current management relies on antibiotic …

Published: June 4, 2026, midnight
Emerging signal transduction pathways and the role of bacterial extracellular vesicles linked to the pathogenesis of endometriosis.

Endometriosis is defined as the ectopic proliferation of endometrial cells. Aberrant signal transduction is present in ectopic endometriotic lesions, and bacteria also contributes to the development of endometriosis by transmitting …

Published: June 4, 2026, midnight
TICAM1-Mediated TLR3/TLR4 Signaling Promotes Endometrial Stromal Cell Proliferation, Migration, and Invasion in Endometriosis via IRF3/IFN-β Axis.

Endometriosis (EMs) is an estrogen-dependent inflammatory disease characterized by the presence of endometrial-like tissue outside the uterine cavity, yet its precise pathogenesis remains incompletely elucidated. TICAM1, a key adaptor protein …

Published: June 4, 2026, midnight
RE-1 silencing transcription factor is reduced in endometriosis and uterine deletion in mice alters progesterone responsiveness.

Endometriosis is a steroid-dependent gynecologic disease characterized by progesterone (P4) resistance, subfertility/infertility, and pelvic pain; however, the molecular mechanisms underlying impaired P4 responsiveness in endometriosis tissue are not fully understood. …

Published: June 3, 2026, midnight
Inside the obturator canal: robotic ganglion cyst decompression.

Obturator nerve compression is an uncommon cause of groin and medial thigh pain. Ganglion cysts extending into the obturator foramen are rare and usually managed via open or orthopaedic approaches. …

Published: June 2, 2026, midnight
The needs, preferences, and priorities for supportive healthcare in people living with endometriosis: A qualitative exploratory study.

Although pain, poor quality of life and symptoms of anxiety and depression are common in people with endometriosis, consumer views regarding supportive care needs are limited. Using a descriptive phenomenological …

Published: June 2, 2026, midnight
Analysis of adverse events following COVID-19 vaccination and infection: A retrospective, comparative cohort study using a claims database from Discovery Health, a managed care organisation in South Africa.

Adverse events following COVID-19 vaccination have been studied extensively in recent years. However, there remains a paucity of data directly comparing adverse events among COVID-19 vaccinees and individuals with SARS-CoV-2 …

Published: June 2, 2026, midnight
Endometriosis-Associated Infertility: A Review of Pathophysiological Mechanisms and Current Treatment Strategies.

Background: Endometriosis affects 10-15% of reproductive-aged women and is a leading cause of infertility through anatomical, inflammatory, and molecular mechanisms. Objective: This review synthesizes current evidence on the pathophysiology of …

Published: June 2, 2026, midnight
Endometrial BCL6 Expression and Reproductive Outcomes in Infertile Women: A Systematic Review.

Background/Objectives: Endometrial B-cell lymphoma 6 (BCL6) overexpression has been proposed as a marker of progesterone resistance, occult endometriosis, and endometrial dysfunction in infertile women. Its possible association with reproductive outcomes …

Published: June 2, 2026, midnight
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