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The enzymatic mechanisms of lactylation and its role in gynecological diseases: a comprehensive review.

Lysine lactylation (Kla) is a novel form of post-translational modification. It utilizes lactate as its core substrate. Through an enzymatic regulatory network, it mediates modifications of both histones and non-histone …

Published: April 30, 2026, midnight
Uterine and Sigmoid Colon Perforation Following Hysteroscopy-Guided Microwave Endometrial Ablation (MEA) in a Patient With a Bicornuate Uterus and Multiple Myomas: A Case Report.

In Japan, the microwave endometrial ablation system (MEA, Microsulis PLC, Waterlooville, UK) is the most widely used device for endometrial ablation and is considered a minimally invasive, uterus-preserving treatment for …

Published: April 29, 2026, midnight
[Investigation of pharmacological regimens combined with focused ultrasound ablation surgery for alleviating dysmenorrhea in extrinsic adenomyosis].

Objective: To investigate optimal long-term medication regimens combined with focused ultrasound ablation surgery (FUAS) for alleviating dysmenorrhea in patients with extrinsic adenomyosis. Methods: A retrospective research enrolled patients with extrinsic …

Published: April 29, 2026, midnight
Clinically Validated Leptin Receptor as a Target for Liposomal Delivery of Metformin in Endometriosis Therapy.

Endometriosis is a common, estrogen-driven chronic gynecologic disorder defined by the ectopic growth of endometrial-like tissue within the peritoneal cavity. Existing treatment options, primarily surgery and hormonal therapy, are limited …

Published: April 29, 2026, midnight
Multi-ancestry genome-wide association and integrated multi-omics analyses of endometriosis and its clinical manifestations.

Endometriosis is a chronic systemic disease affecting ~10% of women, yet its genetic basis and molecular mechanisms remain poorly understood. Hence, here we conducted a genome-wide association study of endometriosis …

Published: April 29, 2026, midnight
Is endometriosis associated with poor sleep quality? A meta-analysis.

BackgroundEndometriosis is a hormone-driven systemic inflammatory condition characterized by endometrial-like lesions which grow throughout the body affecting up to 15% of women worldwide with symptoms including chronic pain, infertility, and …

Published: April 29, 2026, midnight
Performance of Nonaugmented Routine Pelvic Ultrasound for Deep Endometriosis Using Static 2024 SRU Consensus Criteria: A Multireader Study.

To decrease the existing diagnostic delay of pelvic endometriosis, the Society of Radiologists in Ultrasound (SRU) has proposed consensus criteria using augmented pelvic ultrasound (APU) technique and reporting guidelines based …

Published: April 29, 2026, midnight
Clear cell carcinoma developed on hepatic endometriosis: a case report and review of the literature.

Endometriosis is a chronic estrogen-dependent disorder that is generally localized in the pelvis affecting up to 10% of women in the reproductive age. Extra-pelvic locations are estimated to 9% of …

Published: April 29, 2026, midnight
Advancing the frontiers of phytotherapy: a comprehensive review of botanical interventions targeting mitochondrial quality control to ameliorate endometriosis.

Endometriosis (EMs) is a gynecological disorder affecting women of reproductive age. It is characterized by the ectopic implantation and infiltration of endometrial-like tissue and is associated with significant effects on …

Published: April 29, 2026, midnight
Pulmonary endometriosis successfully treated with percutaneous radiofrequency ablation: report of two cases.

Pulmonary endometriosis (PE) is an unusual cause of catamenial hemoptysis, with only a small proportion of endometriosis cases involving the thorax. Standard management often involves surgical resection combined with hormonal …

Published: April 28, 2026, midnight
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