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Leveraging epigenetic aberrations in the pathogenesis of endometriosis: from DNA methylation to non-coding RNAs.

Endometriosis is highly underdiagnosed and undertreated gynecological disorder, with diagnosis often delayed by 8-12 years. This delay can have serious consequences including infertility. Currently, the gold standard for endometriosis diagnosis …

Published: July 28, 2025, midnight
Stage-specific autophagy dynamics in reproductive processes and associated disorders.

Autophagy is a highly conserved eukaryotic process that degrades cytoplasmic material within lysosomes, and plays a crucial role in cellular development, function and homeostasis. Recent studies have increasingly revealed the …

Published: July 28, 2025, midnight
Membrane Progesterone Receptor Beta Regulates the Decidualization of Endometrial Stromal Cells in Women with Endometriosis.

Endometriosis is a disorder characterized by the presence of endometrial tissue outside the uterus, leading to dyspareunia, chronic pelvic pain, dysuria, and infertility. The latter has been related to implantation …

Published: July 28, 2025, midnight
Association of elevated ACSL4 expression with impaired endometrial receptivity in endometriosis and restoration by ACSL4 inhibitor PRGL493.

This study investigated the role of ACSL4 in endometrial receptivity disorders in endometriosis (EMs) and evaluated PRGL493, an ACSL4 inhibitor, as a potential therapeutic target. Bioinformatic analysis identified ACSL4 as …

Published: July 27, 2025, midnight
Interplay of Oxidative Stress, Autophagy, and Rubicon in Ovarian Follicle Dynamics: Orchestrating Ovarian Aging.

Organ functions generally decline with age, but the ovary is a prototypical organ that undergoes functional loss over time. Autophagy plays a crucial role in maintaining organ homeostasis, and age-related …

Published: July 27, 2025, midnight
Mapping deep endometriosis in patients with ovarian endometriomas according to the #Enzian classification: a single-center retrospective analysis.

Endometriosis is a multifactorial disease that affects mainly women of reproductive age. It is unclear whether each form of pelvic endometriosis is an independent entity and whether a spatial relationship …

Published: July 25, 2025, midnight
The Great Mimicker: Extragonadal Endometriosis Presenting as an Appendiceal Mass and Acute Appendicitis.

A 45-year-old female presented to the Emergency Department with acute right lower quadrant (RLQ) pain. Her past medical history was significant for heavy menstrual bleeding and moderate dysmenorrhea, though a …

Published: July 25, 2025, midnight
Research uses AI to find pathologic and genetic basis for worse outcome of endometrial cancer in Black women - Medical Xpress

Research uses AI to find pathologic and genetic basis for worse outcome of endometrial cancer in Black women Medical Xpress

Published: July 24, 2025, 2:29 p.m.
Regeneron Announces the 2025 Winners of the Regeneron Prize for Creative Innovation - The Manila Times

Regeneron Announces the 2025 Winners of the Regeneron Prize for Creative Innovation The Manila Times

Published: July 24, 2025, 11:47 a.m.
Regeneron Prize 2025: MIT and Harvard Scientists Win $50K Each for Groundbreaking Medical Research Ideas - Stock Titan

Regeneron Prize 2025: MIT and Harvard Scientists Win $50K Each for Groundbreaking Medical Research Ideas Stock Titan

Published: July 24, 2025, 11:30 a.m.
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