Recent advances in the development of 17beta-hydroxysteroid dehydrogenase inhibitors.
The family of 17β-hydroxysteroid dehydrogenases (17β-HSDs) occupies a prominent place due to its number of isoforms, which carry out a bidirectional transformation (reduction of a steroid carbonyl to alcohol and …
Symptomatic Uterine Rudiments in Adolescents and Adults with Mayer-Rokitansky-Küster-Hauser Syndrome (MRKHS): Management and Outcomes.
Background: Women with an aplastic uterus (ESHRE/ESGE classification) or Müllerian agenesis (ASRM MAC 2021) might present with functional uterine remnants. Our study aimed to report the clinical course of symptomatic …
Elective uterine preservation: a novel concept to tackle reproductive ageing. Fertility preservation beyond ovaries.
With a growing number of women in developed countries having children later in life, it is time to rethink women's reproductive health. This trend of 'delayed parenthood' reflects a complex …
Upregulated let-7 expression in the follicular fluid of patients with endometriomas leads to dysfunction of granulosa cells through targeting of IGF1R.
What molecular mechanisms underlie the decline in ovarian reserve as the number and quality of oocytes decrease in patients with ovarian endometriomas (OEM)?