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Establishment of a Novel In Vitro and In Vivo Model to Understand Molecular Carcinogenesis of Endometriosis-Related Ovarian Neoplasms.

The molecular mechanisms through which endometriosis-related ovarian neoplasms (ERONs) develop from benign endometrioma remain unclear. It is especially a long-standing mystery why ovarian endometrioma has the potential to develop into …

Published: Feb. 25, 2025, midnight
Illness perceptions among individuals with endometriosis and their longitudinal associations with psychological distress and pain.

This study examined the illness perceptions held by individuals living with endometriosis, and their associations with psychological distress and chronic pain, over time. At baseline, 408 participants provided demographic and …

Published: Feb. 24, 2025, midnight
Construction organoid model of ovarian endometriosis and the function of estrogen and progesterone in the model.

Endometriosis is a refractory estrogen-dependent gynecological disease in which ovarian endometriosis(OE) is the most common, and the main cell components are endometrial epithelial cells and stromal cells. However, constructing ectopic …

Published: Feb. 24, 2025, midnight
Thymic stromal lymphopoietin contributes to endometriotic lesion proliferation and disease-associated inflammation.

Endometriosis is a chronic disorder in which endometrial-like tissue presents outside the uterus. Patients with endometriosis have been shown to exhibit aberrant immune responses within the lesion microenvironment and in …

Published: Feb. 24, 2025, midnight
Endometriosis in Adolescence: A Narrative Review of the Psychological and Clinical Implications.

Endometriosis is a chronic, inflammatory condition where endometrial-like tissue grows outside the uterus, affecting around 10% of women of reproductive age. This condition is associated with debilitating symptoms, including dysmenorrhea, …

Published: Feb. 24, 2025, midnight
Suppression of endometriosis by miRNA-34a via inhibition of matrix metalloproteinase-2: An alternative pathway to impede invasion.

Matrix metalloproteinases (MMPs) cleave proteins of extracellular matrix thus facilitating cellular invasion and cancer progression. High MMP-2 activity is frequently reported in several diseases including endometriosis and cancer. Endometriosis, though …

Published: Feb. 24, 2025, midnight
Endometriosis Presenting as a Rare Cause of Intestinal Perforation: A Case Report With Literature Review.

This case report details a 39-year-old woman with a history of endometriosis who presented with severe abdominal pain, vomiting, and nausea, leading to a diagnosis of intestinal perforation caused by …

Published: Feb. 23, 2025, midnight
Can Anticancer Drugs Be A Promising Candidate for The Treatment of Endometriosis?

Endometriosis, a benign gynecological disorder affecting 10-15% of women during their reproductive years, is characterized by the growth of endometrial tissue outside the uterus. Despite its prevalence, the exact pathophysiology …

Published: Feb. 23, 2025, midnight
Primary Low-Grade Endometrial Stromal Sarcoma of the Ovary Arising From Endometriosis: A Case Report.

Low-grade endometrial stromal sarcoma (LGESS) is a rare mesenchymal tumor of female genital tract malignancies. While it primarily arises in the uterus, extrauterine cases, including those originating in the ovary, …

Published: Feb. 23, 2025, midnight
A quality-of-life meta-analysis comparing pre- and postoperative symptoms in women undergoing colorectal resection for deep infiltrating endometriosis.

Deep infiltrating endometriosis (DIE) may involve the rectum or colon and is associated with pain, gastrointestinal dysfunction and reduced quality of life (QoL). While hormonal treatment may be effective, surgical …

Published: Feb. 22, 2025, 12:15 a.m.
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