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Comprehensive Analysis of Vaginal and Gut Microbiome Alterations in Endometriosis Patients.

Endometriosis (EMS) is a chronic gynecological disorder with unclear pathogenesis. While the vaginal and gut microbiomes are known to influence EMS, few studies have analyzed both microbiomes integrally. This study …

Published: Dec. 30, 2025, midnight
Longitudinal ultrasound-based follow up of non-surgically treated endometriosis using #Enzian classification.

This study aimed to compare clinical and ultrasound outcomes over 24 months in premenopausal women with ultrasound-diagnosed endometriosis/adenomyosis, never treated surgically, and managed with or without hormonal therapy. We specifically …

Published: Dec. 29, 2025, midnight
Appendiceal endosalpingiosis: a rare case with potential implications for gynecological malignancy.

Appendiceal endosalpingiosis is an exceedingly rare histopathologic finding with uncertain clinical significance and unknown implications for management. Most often, endosalpingiosis occurs within ovary, fallopian tube, omentum, and uterus. Previous literature …

Published: Dec. 28, 2025, midnight
PRMT3-mediated FOXO1 arginine methylation exacerbates oxidative stress-induced decidualization defects in the eutopic endometrium of endometriosis.

Endometriosis is a hormone dependent disease that often accompanies infertility. At present, the incidence rate of endometriosis is on the rise, but its pathogenesis and the mechanism leading to fertility …

Published: Dec. 27, 2025, midnight
In Situ Characterization and Deep Profiling of Engineered Multispecific Nanoparticle Metabolite Coronas for Precise Serum Diagnostics.

Upon exposure to biofluids, engineered nanoparticles (NPs) spontaneously form reproducible biomolecular coronas via selective diverse biomolecule adsorption. The corona characterization of metabolites poses greater analytical challenges than proteins due to …

Published: Dec. 26, 2025, midnight
Molecular Imaging Advances in Endometriosis: The Promise of Radiopharmaceuticals.

Endometriosis is a highly prevalent, chronic gynecological disorder characterized by the ectopic presence of endometrial-like tissue, driving significant morbidity and chronic pelvic pain. Pathologically, it is increasingly recognized as a …

Published: Dec. 25, 2025, midnight
First live births after adipose-derived stem cells and platelet-rich plasma intraovarian administration.

This report describes two women aged 45 and older who achieved live births following intraovarian administration of a novel combination of mechanically processed adipose nanofat rich in adipose-derived stem cells …

Published: Dec. 25, 2025, midnight
Immunological Causes of Infertility: Diagnostic Perspectives.

From an immunological perspective, infertility mechanisms encompass not only fertilization but also implantation, as well as both early and late pregnancy loss. Growing attention is being directed towards the influence …

Published: Dec. 25, 2025, midnight
Targeting inflammation in endometriosis: emerging therapeutic options.

Endometriosis is a chronic, estrogen-dependent inflammatory disease affecting up to 10% of reproductive-aged women. Current therapies are predominantly hormone-based and offer symptomatic relief without correcting the immune dysregulation and inflammation …

Published: Dec. 24, 2025, midnight
Molecular and Immune Microenvironmental Changes Across Endometrial Lesions: A Comprehensive Immunohistochemical and Clinical Analysis of Progression From Benignity to Carcinoma.

Adenomyosis and endometriosis are estrogen-driven disorders with a recognized potential for malignant transformation, particularly through atypical endometriosis. The molecular and immune mechanisms underlying this progression remain incompletely understood. However, clinical …

Published: Dec. 24, 2025, midnight
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