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ATOPE study protocol: a randomised controlled trial comparing cystectomy and plasma vapourisation in endometriomas under 6 cm, with an observational arm for sclerotherapy in larger cysts.

The Ablative Technique Options for Preserving fertility in Endometrioma study is a prospective, monocentric clinical study that combines a randomised controlled trial comparing cystectomy and plasma vapourisation for endometriomas measuring …

Published: April 28, 2026, midnight
Preserving Fertility in Young Women: Triple-Step Strategy for Managing Giant Endometriomas With Minimal AMH Decline-A Case Report.

Endometriomas are a frequent cause of infertility in reproductive-aged women, often requiring surgery. However, cystectomy for large endometriomas may reduce ovarian reserve, as indicated by decreased anti-Müllerian hormone (AMH) levels. …

Published: April 28, 2026, midnight
Characterization of elevated levels of endometrial renin-angiotensin system components suggest a role in endometrial repair.

Each month, the endometrium is shed, regenerated, and transformed in response to changing hormone levels. These processes occur in a tightly regulated manner, and irregularities are linked with reproductive health …

Published: April 28, 2026, midnight
Assessment of Duration of Sliding Sign in Routine Pelvic Ultrasound Studies.

This study aims to evaluate the implementation of the uterine sliding sign in routine pelvic ultrasound examinations for improving the diagnosis of deep endometriosis. A retrospective analysis was conducted at …

Published: April 27, 2026, midnight
The relationship between psychological factors and pain in endometriosis.

Endometriosis is a prevalent condition characterized by persistent pelvic pain, which leads to distress and reduced quality of life. Currently, there is limited research examining the psychological factors associated with …

Published: April 27, 2026, midnight
Endocrine roles of vitamin D in female reproduction: Mechanisms and clinical implications.

Vitamin D a fat-soluble steroid hormone signals through Vitamin D Receptors (VDRs) located throughout the ovaries, uterus, placenta, hypothalamus, and pituitary gland, influencing immune regulation and female reproductive physiology. This …

Published: April 27, 2026, midnight
NET-DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy-Mediated Anoikis Resistance in Endometriosis.

Endometriosis (EMs) features ectopic implantation of endometrial stromal cells (EESCs) and strong anoikis resistance, yet how inflammatory signals reprogram mitochondrial function remains unclear. Here, neutrophil extracellular traps (NETs), particularly their …

Published: April 27, 2026, midnight
Stage-Related Changes in TGF-β Isoforms in PBMC Culture Supernatants in Endometriosis: A Prospective Case-Control Study.

Endometriosis is a chronic inflammatory disease in which transforming growth factor-beta (TGF-β) has been implicated in immune dysregulation, extracellular matrix remodeling, and fibrosis. Data on baseline secretion of TGF-β isoforms …

Published: April 27, 2026, midnight
A comprehensive treatment algorithm for chronic pelvic pain patients: A perspective review and future guidelines.

Chronic pelvic pain is one of the most prevalent syndromes in family medicine, gynecology, and urology. Chronic pelvic pain patients are often misdiagnosed and have unnecessary prolonged suffering. Both misdiagnosis …

Published: April 25, 2026, midnight
Microbiota-metabolite axis in endometriosis: Pathogenic mechanisms and clinical implications.

Growing evidence highlights the role of microbiota, including those of the gut, reproductive tract, and endometrial tissue, as critical functional drivers in the pathogenesis of endometriosis (EM). Studies have revealed …

Published: April 25, 2026, midnight
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