Endometriosis is a chronic, systemic, inflammatory disease characterized by the presence of endometrium-like tissue growing outside of the uterus. One of its main symptoms is chronic pain and inflammation leading …
Sex-related differences influence key biological processes relevant to biomaterials research, including tissue regeneration, immune response, drug metabolism, and relevant diseases. Despite increasing recognition of sex as a critical biological variable, …
This scoping review aims to evaluate recent studies that examine the relationship between dyspareunia and neurophysiologic factors, and to synthesize their results as it pertains to the development and treatment …
Menstrual blood (MB), a biofluid rich in diverse cell types and biomolecules, has emerged as a vital resource for investigating female reproductive health and diseases because of its unique composition …
Infertility has a significant impact on women, affecting them both mentally and physically. Some of the current infertility-related diseases include intrauterine adhesions, endometriosis, polycystic ovary syndrome, primary ovarian insufficiency, and …
We describe the case of a young 42-year-old female who suffered from cyclical right upper quadrant abdominal pain that led to an emergency department visit where an intrahepatic mass was …
Polypoidal rectal endometriosis is a rare and diagnostically challenging manifestation of deep infiltrating endometriosis that may mimic colorectal malignancy, especially in women lacking classical cyclical symptoms. We report such a …
In mammals, insulin-like peptide 3 (INSL3) and its cognate receptor (RXFP2) are reported to be essential regulators of male reproductive physiology. It is also believed that INSL3/RXFP2 signaling has a …
Pelvic inflammatory disease (PID) encompasses a broad range of infection-induced inflammatory disorders of the female upper genital tract, commonly caused by ascending sexually transmitted infections. Diagnosis is often challenging because …
Endometriosis (EMS) is a prevalent estrogen-dependent gynecological disorder characterized by ectopic growth of endometrial tissue. Central to its pathophysiology, peritoneal CD14hi macrophages exhibit a pro-EMS phenotype and drive disease progression. …