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The Great Mimicker: Extragonadal Endometriosis Presenting as an Appendiceal Mass and Acute Appendicitis.

A 45-year-old female presented to the Emergency Department with acute right lower quadrant (RLQ) pain. Her past medical history was significant for heavy menstrual bleeding and moderate dysmenorrhea, though a …

Published: July 25, 2025, midnight
Menopause as a Critical Turning Point in Lipedema: The Estrogen Receptor Imbalance, Intracrine Estrogen, and Adipose Tissue Dysfunction Model.

Lipedema is a chronic, estrogen-sensitive adipose tissue disorder characterized by disproportionate subcutaneous fat accumulation, fibrosis, inflammation, and resistance to fat mobilization. Despite its high prevalence, lipedema remains poorly understood and …

Published: July 23, 2025, midnight
NXF1 suppresses progression of endometrial cancer by interacting with the SRSF3 to regulate SP4 splicing.

Conventional treatments for advanced endometriosis often have limited efficacy due to chemotherapy resistance, recurrence, and metastasis. This study analyzed clinical specimens to investigate the role of NXF1 in endometrial cancer …

Published: July 22, 2025, midnight
Non-Hormonal Strategies in Endometriosis: Targets with Future Clinical Potential.

Endometriosis is a chronic gynecological pathology marked by the aberrant proliferation of tissue analogous to the endometrial lining outside the uterine cavity. This disorder frequently engenders persistent pelvic discomfort, infertility, …

Published: July 17, 2025, midnight
Role of AMP-Activated Protein Kinase (AMPK) in Female Reproduction: A Review.

The adenosine monophosphate (AMP)-activated protein kinase (AMPK) signalling pathway regulates cell metabolism, inflammation and the immune response. This signalling pathway is essential for maintaining reproductive homeostasis and influencing steroidogenesis, implantation, …

Published: July 16, 2025, midnight
The Role of Plant-Based Diets and Personalized Nutrition in Endometriosis Management: A Review.

Endometriosis is a chronic, estrogen-dependent inflammatory condition that affects multiple organ systems and significantly impairs the quality of life in women of reproductive age. While conventional hormonal therapies may alleviate …

Published: July 13, 2025, midnight
Multiple lesions of endometriosis in the small intestine treated by the shaving technique: A case report.

A case is reported of endometriosis present in several areas of the small intestine, successfully treated by excision using the conservative technique of shaving the intestinal wall. A 30-year-old woman …

Published: July 13, 2025, midnight
Spontaneous umbilical endometriosis.

Endometriosis is defined as the presence of endometrial tissue (glands and stroma) outside the uterine cavity. Various organs can be affected, including the skin. Umbilical endometriosis is the most common …

Published: June 25, 2025, midnight
Association between endometriosis and endometrial polyps: a systematic review and meta-analysis.

Endometriosis and endometrial polyps are oestrogen-dependent conditions that frequently co-occur, yet their combined prevalence remains unclear. This study synthesized data on the prevalence of endometrial polyps in women with endometriosis …

Published: June 22, 2025, midnight
Appendicitis with Appendicular Phlegmon Secondary to Endometriosis.

Acute appendicitis is a common surgical emergency, however endometriosis in an appendix is a rare phenomenon. In this case report, we describe a 34-year-old woman who visited a teaching hospital …

Published: May 2, 2025, midnight
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