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The overlooked link between reproductive system disorders and depression: a cohort study in 2 million women.

Depression rates are higher in women, especially during periods of hormonal fluctuation. Reproductive system disorders (RSDs), which often disrupt hormonal balance, may contribute to this mental health burden. Despite their …

Published: Nov. 21, 2025, midnight
Bioinformatic analysis and validation of candidate genes in the eutopic endometrium reveal differential expressions in diffuse adenomyosis, endometrioma, and their co-existence.

Adenomyosis and endometriosis are hormone-dependent benign gynecological disorders with overlapping features suggesting that they may share a common origin despite being considered distinct entities. This study compares the expression of …

Published: Nov. 21, 2025, midnight
MiRNome alterations drive the malignant transformation of endometriosis into endometriosis-correlated ovarian cancer.

Endometriosis (EMS) is a chronic gynecological condition affecting 6-10% of reproductive-age women. These lesions, albeit of benign nature, present cancer-like features, and may progress to epithelial ovarian cancer (EOC) through …

Published: Nov. 21, 2025, midnight
Innovations in Robotic Surgery: Fertility Sparing Stage IV Endometriosis Resection with the DaVinci Single-Port (SP) System.

To show a complex fertility sparing resection of stage IV endometriosis with the DaVinci Single-Port (SP) Robot system, and to provide tips and tricks for surgical skill and efficiency when …

Published: Nov. 21, 2025, midnight
The Effects of Emotional Freedom Technique on Pelvic Pain and Quality of Life in Women Diagnosed with Endometriosis: A Randomized Controlled Trial.

Objective: The primary goal of treatment for endometriosis (EMS), where pelvic pain is the most significant symptom, is the symptom alleviation. Medical treatment is typically employed until menopause or until …

Published: Nov. 21, 2025, midnight
Long-term risk of psychiatric disorders in women with endometriosis: A retrospective cohort study.

Endometriosis is a chronic, estrogen-dependent condition associated with substantial physical and psychological burden. Although psychiatric comorbidities are frequently reported, large-scale real-world data remain limited.

Published: Nov. 21, 2025, midnight
Impact of Physical Rehabilitation on Endometriosis and Adenomyosis-Related Symptoms: A Systematic Review and Meta-Analysis.

Objectives: The aim of this study is to summarize recent evidence of the effectiveness of rehabilitation interventions in managing symptoms related to endometriosis and adenomyosis. Methods: The review protocol was …

Published: Nov. 21, 2025, midnight
Establishment and Characterization of a New Immortalized Human Adenomyosis Epithelial-Like Cell Line, tAEC21†.

Adenomyosis occurs when endometrial glands and stroma grow within the uterine myometrium. As a clinically significant disease, adenomyosis causes substantial pelvic pain and heavy menstrual bleeding. It remains understudied due …

Published: Nov. 20, 2025, midnight
A cross-sectional analysis of brain structure, pain behaviors, and mental health in persons with surgically confirmed endometriosis.

Endometriosis is a highly prevalent and often painful gynecological condition that can emerge in adolescence and can be experienced throughout a person's lifetime. This cross-sectional investigation performed structural brain imaging …

Published: Nov. 20, 2025, midnight
Endometriosis - on the intersection of modern environmental pollutants and ancient genetic regulatory variants.

Endometriosis is a chronic, estrogen-driven inflammatory disorder affecting approximately 10% of reproductive-aged women globally. Despite increasing genomic insights into advanced-stage disease, the genetic underpinnings of early-stage endometriosis remain poorly understood, …

Published: Nov. 20, 2025, midnight
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