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High-Resolution Spatial Transcriptomics Reveals Fibroblast and Neuroimmune Microenvironments in Endometriosis Lesions.

Endometriosis is a chronic, systemic, inflammatory disease characterized by the presence of endometrium-like tissue growing outside of the uterus. One of its main symptoms is chronic pain and inflammation leading …

Published: Aug. 25, 2025, midnight
MMP2/TIMP2 ratio as a measurable indicator for differentiating diffuse adenomyosis, ovarian endometriosis, and their co-existence.

Adenomyosis and endometriosis, two common estrogen-dependent benign gynecological disorders usually present with overlapping symptoms, such as pain and infertility. These two conditions often co-exist and are associated with poor reproductive …

Published: Aug. 24, 2025, midnight
NR4A1 Acts as a Nutrient Sensor That Inhibits the Effects of Aging.

Orphan nuclear receptor 4A1 (NR4A1) is a member of the NR4A subfamily that was initially discovered as an intermediate early gene expressed in response to stressors, including inflammatory agents. This …

Published: Aug. 21, 2025, midnight
Perimenopause and Fibroids, Endometriosis - yahoo.com

Perimenopause and Fibroids, Endometriosis yahoo.com

Published: Aug. 20, 2025, 9:03 a.m.
Factors Influencing Chronic Pain After Hysterectomy for Uterine Fibroids: Development and Validation of a Nomogram Prediction Model.

To develop and validate a nomogram prediction model for chronic pain after hysterectomy for uterine fibroids.

Published: Aug. 18, 2025, midnight
Unveiling the vital role of OGG1 in inflammation, vascular endothelial damage, and cell death in obstetric and gynecological diseases.

The DNA repair enzyme 8-oxoguanine DNA glycosylase-1 (OGG1) plays a crucial role in the initiation of DNA base excision repair pathway by recognizing and excising the oxidative base lesions including …

Published: Aug. 14, 2025, midnight
Single-Cell Profiling Reveals Altered Endometrial Cellular Features Across the Menstrual Cycle in Endometriosis Patients.

Endometriosis is a chronic, estrogen-dependent condition affecting over 190 million women globally, characterized by the ectopic presence of endometrial-like tissue that leads to inflammation, pain, and infertility. Despite its prevalence, …

Published: Aug. 14, 2025, midnight
AntiCD44 antibody-conjugated gold nanoparticles for targeted photothermal therapy of endometriotic cells.

Endometriosis is a chronic gynecologic disease that needs newer and safer treatments. The proposed work aims to develop a nanosystem based on gold nanoparticles (AuNPs) to actively target human endometriosis …

Published: Aug. 13, 2025, midnight
Efficacy and Safety of Personalized Percutaneous Single-Probe Cryoablation Using Liquid Nitrogen in the Treatment of Abdominal Wall Endometriosis.

Background: Abdominal wall endometriosis (AWE) is a rare but debilitating condition, often occurring in surgical scars after Caesarean sections. It is characterized by cyclic pain and a palpable mass, significantly …

Published: Aug. 13, 2025, midnight
Myelofibrosis Trials: Diverging Narratives on Enrollment, Endpoint Clarity, and Safety Data - AInvest

Myelofibrosis Trials: Diverging Narratives on Enrollment, Endpoint Clarity, and Safety Data AInvest

Published: Aug. 11, 2025, 3:12 p.m.
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