Endometriosis is a chronic, oestrogen-responsive inflammatory disease characterised by endometrial-like tissue outside the uterine cavity. Because retrograde menstruation is common, lesion establishment probably requires cellular competence and a permissive ectopic …
Cardiovascular disease (CVD) remains the leading cause of mortality globally. Emerging evidence indicates that cardiovascular risk in women is frequently underestimated, underscoring the importance of recognizing sex-specific contributors. Endometriosis is …
Ovarian endometriosis is a chronic inflammatory disease characterized by extensive tissue remodeling and fibrosis, which significantly impacts female reproductive health. This study demonstrates that ectopic endometrium (Ect) in patients with …
Daughters of women with endometriosis are known to be at increased risk of developing this disease. Using a mouse model, we demonstrate uterine dysfunction reminiscent of endometriosis patients can also …
Endometriosis is a systemic inflammatory disease in which immune dysregulation and oxidative stress contribute to pain and impaired quality of life. This study aimed to examine whether antioxidant and inflammatory …
Background: Endometriosis affects 10% of reproductive-aged women globally and is one of the major causes of infertility. It is a debilitating, chronic condition with an average diagnostic delay of up …
Endometriosis is a chronic inflammatory and estrogen-dependent disease in which pain remains the leading cause of impaired quality of life. Hormonal therapies constitute the cornerstone of medical management and include …
Endometriosis (EMs) is a chronic gynecological disease with poorly understood pathogenesis. This study integrated lipidomics and transcriptomics to systematically investigate aberrant sphingolipid metabolism in EMs, aiming to identify pathogenic mechanisms …
Human papillomavirus (HPV) infection is a necessary but insufficient cause of cervical cancer (CC) and reflects a long-standing host-virus equilibrium shaped by immune control, viral persistence, and latency. The transition …
Background/Objectives: Endometriosis is a chronic gynecological condition affecting approximately 10% of women of reproductive age and is associated with chronic pain, fatigue, infertility, and reduced quality of life. Beyond its …