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Engineered womb lining model opens a window into embryo implantation - News-Medical

Engineered womb lining model opens a window into embryo implantation News-Medical

Published: Dec. 24, 2025, 1:41 a.m.
Predictive value of MR imaging IVIM and T2 mapping in malignant transformation of endometriosis.

This study aims to explore the value of MRI intravoxel incoherent motion (IVIM) combined with T2 mapping in predicting the malignancy of endometriosis (EM) and construct a noninvasive preoperative risk …

Published: Dec. 24, 2025, midnight
Feasibility and clinical value of virtual reality based on 3D model in colorectal endometriosis for surgical planning.

Colorectal endometriosis (CRE) is one of the most severe forms of deep pelvic endometriosis with a high risk of major postoperative complications. While pelvic MRI is the gold standard for …

Published: Dec. 24, 2025, midnight
Endometriosis: From Genes to Global Burden.

Endometriosis has a significant impact on the social, psychological, psychosomatic, and physical aspects of women's lives. There is increasing evidence that endometriosis has to be seen as a systemic and …

Published: Dec. 23, 2025, midnight
The role and underlying mechanisms of Qi Gong Wan in enhancing the endometrial receptivity of a rat model with polycystic ovary syndrome - Frontiers

The role and underlying mechanisms of Qi Gong Wan in enhancing the endometrial receptivity of a rat model with polycystic ovary syndrome Frontiers

Published: Dec. 22, 2025, 5:04 p.m.
Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol-Driven WNT7B Suppression.

Adult endometrial glands undergo cyclic regeneration and development during the menstrual cycle. Their secretions are vital for endometrial functions and early pregnancy, yet the mechanisms controlling gland development are not …

Published: Dec. 22, 2025, midnight
Perspectives and Priorities for Endometriosis Multidisciplinary Team Care in Australia: A Qualitative Mixed-Methods Study Involving Patients, Caregivers and Health Professionals.

Endometriosis is a chronic condition affecting 1 in 7 women, girls, and gender-diverse individuals in Australia. It significantly impacts daily life, causing pain, psychological distress and productivity loss. Multidisciplinary team …

Published: Dec. 21, 2025, midnight
Pharmacokinetic-Pharmacodynamic Modeling and Simulation of Merigolix, a Nonpeptide Gonadotropin-Releasing Hormone Antagonist.

Gonadotropin-releasing hormone (GnRH) antagonists inhibit estrogen synthesis and secretion, making them promising treatment options for estrogen-dependent diseases, such as endometriosis. This study developed a population pharmacokinetic/pharmacodynamic (PK/PD) model for merigolix, …

Published: Dec. 20, 2025, midnight
Non-Invasive Diagnosis of Endometriosis by Questionnaires in Patients Using Contraception.

Background/Objectives: The assessment of endometriosis (EMS)-associated pain is important, but only very few studies address the potential use of questionnaires for non-invasive prediction of the disease. Methods: In a prospective …

Published: Dec. 20, 2025, midnight
EGR1 promotes ferroptosis in endometriosis through transcriptional activation of HMOX1.

Endometriosis (EM) affects approximately 10% of women of reproductive age and remains a prevalent estrogen-dependent gynecological disorder with limited therapeutic efficacy and high recurrence rates. Ferroptosis-an iron-dependent, non-apoptotic form of …

Published: Dec. 19, 2025, midnight
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