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Pharmacokinetic-Pharmacodynamic Modeling and Simulation of Merigolix, a Nonpeptide Gonadotropin-Releasing Hormone Antagonist.

Gonadotropin-releasing hormone (GnRH) antagonists inhibit estrogen synthesis and secretion, making them promising treatment options for estrogen-dependent diseases, such as endometriosis. This study developed a population pharmacokinetic/pharmacodynamic (PK/PD) model for merigolix, …

Published: Dec. 20, 2025, midnight
Non-Invasive Diagnosis of Endometriosis by Questionnaires in Patients Using Contraception.

Background/Objectives: The assessment of endometriosis (EMS)-associated pain is important, but only very few studies address the potential use of questionnaires for non-invasive prediction of the disease. Methods: In a prospective …

Published: Dec. 20, 2025, midnight
Prediction of MBS Item Codes for Endometriosis Surgery Using Transvaginal Ultrasound.

In March 2022, updates in the Australian Medicare Benefits Schedule relating to endometriosis surgery were made relating to item numbers 35637, 35631 and 35632 (division of 35638) and 35641. Updated …

Published: Dec. 19, 2025, midnight
Perceptions of endometriosis surgery on TikTok: quality and implications for patient counselling.

TikTok is a popular platform for sharing health experiences, including those related to endometriosis. However, the quality and tone of the surgical information shared remain unclear.

Published: Dec. 19, 2025, midnight
Correlation between Polycomb repressive complex proteins and epithelial-mesenchymal transition-associated genes in endometriotic tissues.

Endometriosis is a condition in which functional endometrial glands and stroma are found to grow outside the uterine cavity that can lead to symptoms like dysmenorrhea, dyspareunia, adhesions, and infertility. …

Published: Dec. 19, 2025, midnight
EGR1 promotes ferroptosis in endometriosis through transcriptional activation of HMOX1.

Endometriosis (EM) affects approximately 10% of women of reproductive age and remains a prevalent estrogen-dependent gynecological disorder with limited therapeutic efficacy and high recurrence rates. Ferroptosis-an iron-dependent, non-apoptotic form of …

Published: Dec. 19, 2025, midnight
The outcomes of laparoscopic surgeries for urinary bladder and vesicouterine pouch endometriosis in the Polish population.

Urinary bladder endometriosis (BE) is a rare but significant condition, which may co-occur with vesicouterine pouch endometriosis (EVUP). Our study examined the outcomes of laparoscopic surgeries for BE and EVUP.

Published: Dec. 19, 2025, midnight
Usage of methods polarization-phase mueller-matrix introscopy for early diagnosis of endometriosis based on study of dehydrated films of peritoneal fluid.

Aim: To assess the effectiveness of early diagnosis of endometriosis using polarization-phase Muller-matrix introscopy methods of scattering dehydrated films of peritoneal fluid.

Published: Dec. 18, 2025, midnight
Sociodemographic and clinical characteristics of patients with endometriosis: a facility-based cross-sectional study from Bangladesh.

Endometriosis, characterized by the presence of endometrial-like tissue outside the uterus is one of the major causes of chronic pelvic pain in women which jeopardize the daily life. This study …

Published: Dec. 18, 2025, midnight
Expression of Concern: Evaluation of CA125 in relation to pain symptoms among adolescents and young adult women with and without surgically-confirmed endometriosis.

Published: Dec. 18, 2025, midnight
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