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Exploring the Immune System's Role in Endometriosis: Insights Into Pathogenesis, Pain, and Treatment.

Endometriosis is a common gynecological condition that usually affects women during their reproductive years. The main goal of this narrative review is to understand the role of the innate and …

Published: July 1, 2025, midnight
Unraveling the Contribution of Estrobolome Alterations to Endometriosis Pathogenesis.

Endometriosis (EMS) is a long-term inflammatory disease. It represents one of the most prevalent gynecological conditions, impacting an estimated 5% of reproductive women. Therefore, endometriosis contributes to substantial worldwide health …

Published: July 1, 2025, midnight
The role of m6A methylation in female reproductive physiology and pathology.

N6-methyladenosine (m6A) is a critical regulator of female reproductive physiology, yet existing reviews have focused predominantly on oocytes. The objective of this review is to systematically evaluate the regulatory effects …

Published: July 1, 2025, midnight
Analysis of Vitamin D and VDR Expression in Women with Advanced Endometriosis: A Case-Control Study in Thailand.

Background: Vitamin D has anti-inflammatory and immunomodulatory properties that may influence the pathophysiology of endometriosis. This study investigated the association between vitamin D levels and endometriosis, and vitamin D receptor …

Published: June 30, 2025, midnight
Changes in the M1/M2 ratio due to andrographolide therapy for deep endometriosis: An experimental study using a BALB/C endometriosis model.

Andrographolide is a compound that serves as an anti-inflammatory agent. M2 macrophages promote the disease, while M1 macrophages inhibit endometriosis progression.

Published: June 30, 2025, midnight
Spontaneous umbilical endometriosis.

Endometriosis is defined as the presence of endometrial tissue (glands and stroma) outside the uterine cavity. Various organs can be affected, including the skin. Umbilical endometriosis is the most common …

Published: June 25, 2025, midnight
The Hidden Danger in Endometriosis: Bilateral Pelvic Abscesses Following Fertility Treatment.

This case report underscores the crucial role of imaging and radiology in the timely diagnosis of a rare but serious complication associated with assisted reproductive technology (ART). A 34-year-old woman …

Published: June 25, 2025, midnight
Matrix Tropism Influences Endometriotic Cell Attachment Patterns.

The initiation of endometriotic lesions is not well understood or characterized because endometriosis is typically diagnosed at an advanced stage. Endometriotic lesions are most often found on pelvic tissues and …

Published: June 23, 2025, midnight
Association between endometriosis and endometrial polyps: a systematic review and meta-analysis.

Endometriosis and endometrial polyps are oestrogen-dependent conditions that frequently co-occur, yet their combined prevalence remains unclear. This study synthesized data on the prevalence of endometrial polyps in women with endometriosis …

Published: June 22, 2025, midnight
Initial and cyclic recruitment of ovarian follicles: a quarter-century update.

A review of advancements in primordial follicle activation and cyclic recruitment research over the past 25 years is presented. The review examines the latest insights into the mechanisms of primordial …

Published: June 18, 2025, midnight
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