Endometriosis is a chronic estrogen-dependent inflammatory disease affecting approximately 10% of women of reproductive age and characterized by ectopic endometrial-like tissue growth. Although traditionally considered a benign gynecological condition, increasing …
Endometriosis, particularly ovarian endometrioma, is associated with a 2-fold increased risk of ovarian cancer (OC), especially the clear cell and endometrioid subtypes. However, the absolute lifetime risk of OC in …
Endometriosis is a prevalent gynecological disorder characterized by chronic inflammation. Pyroptosis, a type of programmed proinflammatory cell death, plays a crucial role in various inflammatory diseases. However, its specific mechanism …
Angiogenesis mediated by vascular endothelial growth factor A (VEGF-A) is essential for physiological vascular remodeling but also drives pathological processes, including tumor growth, ocular neovascularization, and inflammation. Emerging evidence has …
The potential bidirectional causal relationship between endometriosis and serum 25-hydroxyvitamin D has been previously investigated. Nevertheless, the results could be impacted by confounding factors and reverse causality because of the …
Massive abdominal wall defects resulting from radical abdominal wall endometriosis (AWE) resection present a major reconstructive challenge. This study aims to assess feasibility and short-term safety of a standardized retromuscular-onlay …
Ovarian cancer (OC) remains a major global health issue, often diagnosed late and lacking effective screening.
This case report demonstrates the enhanced visualization capabilities of FAPI in visualizing deep infiltrating endometriosis (DIE) lesions compared to ultrasonography and MRI, suggesting its potential as a powerful diagnostic tool …
Unexplained infertility (UI) continues to pose a diagnostic challenge, affecting a considerable proportion of reproductive-aged women. Increasing evidence suggests that oxidative stress (OS) may contribute to impaired female reproductive function. …
To compare the efficacy, safety and tolerability of elagolix with dienogest in women with moderate-to-severe endometriosis-associated pain.