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An Unusual Diagnosis of Inguinal Pain in a Childbearing-Age Woman: An Inflamed Canal of Nuck Cyst With an Abnormal Leiomyomatous Proliferation.

The canal of Nuck cyst is a rare pathology seen in women in the inguinal canal. It is often mistaken for a hernia or a lipoma; however, diagnosis is confirmed …

Published: May 19, 2026, midnight
Single-cell profiling and machine learning identify cuproptosis-related fibroblast subpopulations and fibrogenesis modulator AEBP1 in endometriosis.

Endometriosis is characterized by progressive fibrosis and limited therapeutic options. Cuproptosis, a copper-dependent form of regulated cell death, has been implicated in multiple pathological conditions, but its relevance to fibroblast-mediated …

Published: May 18, 2026, midnight
HSD11B1 suppresses ferroptosis in endometrial stromal cells through the JUND/IL-10 axis to promote endometriosis progression.

Endometriosis (EMs) is a common gynecological disorder characterized by ectopic endometrial tissue growth, leading to chronic inflammation and pelvic pain. Despite its high prevalence, the molecular mechanisms underlying EMs remain …

Published: May 18, 2026, midnight
Cancer-like Hallmarks of Endometriosis: The Role of Estrogen Signaling and Stem Cell Plasticity.

Endometriosis is a chronic estrogen-dependent inflammatory disease affecting approximately 10% of women of reproductive age and characterized by ectopic endometrial-like tissue growth. Although traditionally considered a benign gynecological condition, increasing …

Published: May 18, 2026, midnight
Deciphering the Diagnostic and Natural Therapeutic Implications of Necrosis by Sodium Overload and NK Signatures in Endometriosis Patients.

Endometriosis (EMT) is characterized by a chronic inflammatory disorder in the female reproductive system, posing significant challenges to global women's health. Necrosis by Sodium Overload (NESCO) is a novel immunogenic …

Published: May 18, 2026, midnight
Nuclear factor IX promotes endometriosis progression through transcriptional activation of tetraspanin-2.

Endometriosis is a benign yet aggressive disease characterized by enhanced proliferation and invasion of ectopic endometrial tissue. Identifying upstream regulators that co-regulate these processes will provide novel insights into endometriosis …

Published: May 16, 2026, midnight
Whole genome methylation profiling of menstrual stem cells identifies novel biomarkers for endometriosis.

Endometriosis, despite its high prevalence, is underdiagnosed and poorly managed due to lack of clinically validated biomarkers and pathophysiological insight. Menstrual blood-derived stem cells have been implicated in disease pathogenesis, …

Published: May 16, 2026, midnight
The impact of different energy sources on redox balance during endometriotic cyst laparoscopy.

The aim of the study was to follow the impact of cystectomy and compare bipolar and laser electrocoagulation on prooxidative stress biomarkers and antioxidative capacity. A total of 60 women …

Published: May 14, 2026, midnight
Exploring the mechanism of plastic additives on reproductive disorders based on network toxicology and molecular docking.

Phthalate esters (PAEs) and organophosphate esters (OPEs) are pervasive 20 environmental pollutants with endocrine-disrupting properties. Despite growing 21 evidence linking PAE/OPE exposure to female reproductive disorders, the 22 diseasespecific molecular …

Published: May 14, 2026, midnight
NLRP1 promotes pyroptosis in endometriosis through the NF-κB signaling pathway.

Endometriosis is a prevalent gynecological disorder characterized by chronic inflammation. Pyroptosis, a type of programmed proinflammatory cell death, plays a crucial role in various inflammatory diseases. However, its specific mechanism …

Published: May 14, 2026, midnight
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