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Current Understanding of Endometriosis Pathophysiology and Future Perspectives.

Endometriosis-the growth of uterine-like tissue outside the uterus-is a devastating disease that severely reduces the quality of life of those affected, resulting in missed days from school and work due …

Published: July 30, 2025, midnight
Can the MMP-9/NGAL ratio be a diagnostic biomarker for the diagnosis of endometrioma in infertile patients?

In this study, we aimed to investigate whether serum NGAL, MMP-9 and the MMP-9/NGAL ratio, which are inflammatory markers used for the diagnosis and follow-up of some diseases, can be …

Published: July 30, 2025, midnight
The Gut-Endometriosis Axis: Genetic Mechanisms and Public Health Implications.

Background/Objectives: Endometriosis is a chronic, estrogen-driven gynecological disorder affecting approximately 10% of reproductive-aged women worldwide, with significant physical, psychosocial, and socioeconomic impacts. Recent research suggests a possible involvement of the …

Published: July 30, 2025, midnight
Diagnosis of postpartum depression and associated factors in South Africa: a cohort study of 47,697 women.

About one-third of South African women have clinically significant symptoms of postpartum depression (PPD). Several socio-demographic risk factors for PPD exist, but data on medical and obstetric risk factors remain …

Published: July 29, 2025, midnight
Advances in non-invasive diagnostic tools for endometriosis: A narrative review of the past ten years.

Endometriosis is a chronic condition defined by endometrium-like tissue outside the uterus, with symptoms including pain, infertility, and fatigue. Despite the high prevalence of disease, diagnosis is frequently delayed, in …

Published: July 29, 2025, midnight
Optimizing endometriosis diagnosis and mapping: The important role of advanced transvaginal ultrasound.

Endometriosis is estimated to affect 5%-10% of women of reproductive age, making timely diagnosis essential for initiating treatment, alleviating symptoms, and reducing the risk of disease progression. Unfortunately, the diagnostic …

Published: July 29, 2025, midnight
Leveraging epigenetic aberrations in the pathogenesis of endometriosis: from DNA methylation to non-coding RNAs.

Endometriosis is highly underdiagnosed and undertreated gynecological disorder, with diagnosis often delayed by 8-12 years. This delay can have serious consequences including infertility. Currently, the gold standard for endometriosis diagnosis …

Published: July 28, 2025, midnight
The Role of MRI in Diagnosis and Pre-Surgical Mapping of Endometriosis.

Endometriosis is a chronic multisystem disease caused by the presence of endometrium-like tissue outside the endometrial canal, inciting inflammation and fibrosis. Transvaginal ultrasound (TVUS) and MRI have replaced diagnostic laparoscopy …

Published: July 28, 2025, midnight
A multi-centre study assessing the diagnostic accuracy of ultrasonographic features of the uterosacral ligaments in patients with and without endometriosis.

To assess the diagnostic accuracy of different ultrasonographic features of USLs affected by endometriosis.

Published: July 27, 2025, midnight
The Great Mimicker: Extragonadal Endometriosis Presenting as an Appendiceal Mass and Acute Appendicitis.

A 45-year-old female presented to the Emergency Department with acute right lower quadrant (RLQ) pain. Her past medical history was significant for heavy menstrual bleeding and moderate dysmenorrhea, though a …

Published: July 25, 2025, midnight
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