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Leveraging epigenetic aberrations in the pathogenesis of endometriosis: from DNA methylation to non-coding RNAs.

Endometriosis is highly underdiagnosed and undertreated gynecological disorder, with diagnosis often delayed by 8-12 years. This delay can have serious consequences including infertility. Currently, the gold standard for endometriosis diagnosis …

Published: July 28, 2025, midnight
The Great Mimicker: Extragonadal Endometriosis Presenting as an Appendiceal Mass and Acute Appendicitis.

A 45-year-old female presented to the Emergency Department with acute right lower quadrant (RLQ) pain. Her past medical history was significant for heavy menstrual bleeding and moderate dysmenorrhea, though a …

Published: July 25, 2025, midnight
A Complex Case Report of OHVIRA syndrome: Uterine didelphys, obstructed hemivagina, and renal agenesis.

Obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome, also known as Herlyn-Werner-Wunderlich syndrome, is a rare congenital anomaly resulting from abnormal development of the Müllerian and Wolffian ducts, characterized by …

Published: July 22, 2025, midnight
A Case of Intramural Adenosarcoma With Sarcomatous Overgrowth Associated With Adenomyosis and Endometriosis.

Adenosarcoma is a mixed epithelial and mesenchymal neoplasm composed of a malignant mesenchymal component and a benign Müllerian glandular component. Although the endometrium is the most common primary site, adenosarcoma …

Published: July 21, 2025, midnight
Association between visceral adiposity index and endometriosis: a population-based study.

Obesity and endometriosis are intricately linked. The body mass index (BMI) is commonly used as an indicator of obesity, but it has limitations. The visceral adiposity index (VAI) is a …

Published: July 21, 2025, midnight
Integrated analysis of single-cell and bulk transcriptomic data reveals altered cellular composition and predictive cell types in ectopic endometriosis.

Endometriosis is often diagnosed late and presents significant challenges in clinical treatment. A comprehensive investigation of the cellular classification and composition of endometriosis is essential for studying its diagnosis and …

Published: July 18, 2025, midnight
Co-Occurrence of Endometriosis with Systemic Lupus Erythematosus: Genetic Aspects.

Previous studies have shown that patients with a history of endometriosis have an increased susceptibility for developing a big number of comorbidities, including various autoimmune diseases. Endometriosis is a complex, …

Published: July 16, 2025, midnight
Co-occurrence of endometriosis with psoriasis and psoriatic arthritis: Genetic insights (Review).

Immunological factors appear to play an important role in the development of endometriosis, as evidenced by the aberrant functioning of immune cells often observed in affected women. Although endometriosis is …

Published: July 10, 2025, midnight
Umbilical Endometriosis With Appendiceal Involvement: A Case Report.

Endometriosis is a common disease that affects women worldwide. While it is most commonly located in the pelvis, lesions may occur in other areas of the body. Concurrent umbilical and …

Published: July 7, 2025, midnight
Clinical challenge of benign metastasizing leiomyoma with cardiac and hepatic involvement: A case report.

Benign metastasizing leiomyoma (BML) is a rare disorder occurring in women with a history of uterine leiomyomas and having detection of leiomyomas in extrauterine locations. This case report describes a …

Published: July 7, 2025, midnight
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