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Acute Hemoperitoneum Secondary to Chronic Hematosalpinx: A Diagnostic Challenge in the Setting of a Negative Pregnancy Test.

Acute hemoperitoneum represents a gynecological and surgical emergency with significant morbidity if diagnosis and intervention are delayed. In women of reproductive age, the etiology is most frequently ruptured ectopic pregnancy; …

Published: Nov. 20, 2025, midnight
Colo-Ovarian Fistula With a Background of Endometriosis: A Report of Three Cases.

Patients with endometriosis are at a high risk of developing pelvic inflammatory disease. This case series presents three cases of colo-ovarian fistulas associated with endometriosis, highlighting the potential for conservative …

Published: Nov. 19, 2025, midnight
Online randomised e-hypnotherapy for chronic pelvic pain study (REST): comparing e-hypnotherapy with relaxation and waitlist to improve pain, cost-effectiveness and biopsychosocial outcomes.

Chronic pelvic pain, defined as persistent pain in the structures of the pelvis, is a condition that significantly impacts the health-related quality of life (HRQoL) of up to one-third of …

Published: Nov. 19, 2025, midnight
Per- and polyfluoroalkyl substances exposure and endometriosis risk: Evidence from epidemiologic, network toxicology, and molecular docking.

Although per- and polyfluoroalkyl substances (PFAS) exposure has been linked to endometriosis, this association remains controversial, and the underlying mechanisms are unclear. This study aimed to investigate this relationship and …

Published: Nov. 19, 2025, midnight
The role of mitophagy in female reproductive system diseases: from molecular mechanisms to therapeutic strategies.

Mitophagy is a catabolic mechanism that selectively degrades damaged mitochondria and precisely modulates mitochondrial content, thereby maintaining intracellular homeostasis under stress conditions. To date, most reviews on mitophagy have predominantly …

Published: Nov. 18, 2025, midnight
Cannabidiol and ∆9-Tetrahydrocannabinol in Endometriosis: A Literature Review on Therapeutic Applications and Mechanisms.

Endometriosis is a chronic, inflammatory, and multifactorial disease characterized by the presence of endometrial tissue outside the uterine cavity, often associated with debilitating symptoms. It affects approximately 10% of women …

Published: Nov. 17, 2025, midnight
Cannabis and Endometriosis: When Is an Adverse Effect Not Adverse?

There is growing evidence that people with endometriosis are utilising cannabis, whether legally or illicitly procured, for management of pain and associated symptoms. As such, concerns over cannabis use as …

Published: Nov. 17, 2025, midnight
''Non-Invasive Extracellular Vesicle Biomarkers in Endometriosis, Molecular Signatures Linking Pelvic Inflammation, Oocyte Quality, and IVF Outcomes''.

Endometriosis impairs fertility by interfering with ovarian function, embryonic development, and endometrial receptivity. Extracellular vesicles (EVs) are recognised as non-invasive biomarkers that may indicate biological processes based on their lipid, …

Published: Nov. 17, 2025, midnight
Proteome-wide Mendelian randomization identifies β-nerve growth factor as a target for endometriosis.

Endometriosis is a chronic inflammatory disorder with poorly understood mechanisms. Inflammatory proteins are hypothesized to play a causal role, but evidence remains limited. We performed a 2-sample Mendelian randomization study …

Published: Nov. 16, 2025, midnight
The effect of infertility-related stress on fertility-related quality of life in reproductive-age married women with endometriosis: the mediating role of family resilience.

This study investigated fertility-related quality of life among married women of reproductive age (20-45 years) with endometriosis-associated infertility, focusing on the mediating role of family resilience between infertility-related stress and …

Published: Nov. 16, 2025, midnight
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