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Ovarian reserve integrated damage (ORI) model for predicting ovarian function recovery after laparoscopic ovarian cystectomy for endometriosis: a randomized controlled trial.

Published: Jan. 21, 2026, midnight
The evolution of endometriosis research models: a paradigm shift from immortalized cell lines to organoids†.

Endometriosis is a complex condition affecting 10% of reproductive-age women worldwide, yet its study has long been hindered by the shortcomings of traditional research models. This review aims to propose …

Published: Jan. 19, 2026, midnight
An ultrasound-based machine learning model for predicting pelvic adhesions: A SHAP-enhanced XGBoost approach.

This study is the first to develop and evaluate a machine learning (ML) model for predicting pelvic adhesions based on ultrasound features, utilizing the SHapley Additive Explanations (SHAP) framework for …

Published: Jan. 19, 2026, midnight
Unraveling the VEGF-ETS1 axis: a transcriptomic and single-cell analysis of angiogenesis in endometriosis.

Endometriosis (EM) is a chronic inflammatory gynecological disorder characterized by ectopic endometrial-like lesions, where aberrant angiogenesis is a hallmark driving lesion establishment and progression. However, the transcriptional mechanisms underlying pathological …

Published: Jan. 16, 2026, midnight
Investigation of endothelin-1 receptor antagonist bosentan in a rat endometriosis model.

The study aimed to investigate the roles of endothelin-1 and endothelin receptors in a rat endometriosis model and to demonstrate how bosentan (BOS), an endothelin receptor blocker, could potentially serve …

Published: Jan. 14, 2026, midnight
Development and validation of a nomogram model for predicting natural pregnancy after hysteroscopy and laparoscopy in patients with tubal infertility complicated with pelvic endometriosis.

This study aimed to construct and validate a nomogram for predicting natural pregnancy after hysteroscopy and laparoscopy in patients with tubal infertility and pelvic endometriosis, providing a basis for precise …

Published: Jan. 11, 2026, midnight
The Positive Association Between RCII and Endometriosis and Its Integration into a Clinical Predictive Model: A Cross-Sectional Study.

Studies indicate that endometriosis (EMs) is associated with inflammation and metabolic abnormalities. The Remnant Cholesterol Inflammatory Index (RCII) concurrently reflects both inflammatory and metabolic status. However, the relationship between RCII …

Published: Jan. 8, 2026, midnight
Development of a three-dimensional culture model of endometrium to study embryo-uterine interactions.

Three-dimensional (3D) culture systems provide physiologically relevant models that better replicate in vivo cell architecture and function compared to the conventional two-dimensional cultures. In reproductive biology, 3D models of endometrial …

Published: Jan. 6, 2026, midnight
Evidence for KISS-1 nuclear translocation and PI3K/AKT signaling in the ultrastructurally and morphometrically analyzed human endometriosis.

Endometriosis is a common estrogen-dependent disease marked by ectopic endometrial growth. Although the PI3K/AKT and kisspeptin pathways are known to regulate endometrial homeostasis, their interplay in disease progression remains unclear. …

Published: Jan. 6, 2026, midnight
Artificial Intelligence in Gynecologic Imaging.

What was done? A review of artificial intelligence (AI) applications for the imaging of uterine fibroids, endometriosis, and adenomyosis. What was found? AI models can assist with the recognition, segmentation, …

Published: Jan. 6, 2026, midnight
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