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Efficacy and Safety of 48-Week Low-Dose Dienogest Treatment in Patients with Endometriosis-Associated Dysmenorrhea: A Randomized, Open-Label, Parallel-Group Trial.

Dienogest (DNG) is widely used to manage endometriosis-associated pain; however, long-term data comparing low and standard doses are limited. Therefore, this study aimed to evaluate the efficacy and safety of …

Published: Oct. 24, 2025, midnight
Effects of hormonal treatment on the expression of collagen type I, matrix metalloproteinase-1, and tissue inhibitor of metalloproteinases-1 in endometriosis.

Endometriosis is an estrogen-dependent disease, and hormonal treatment is the most common treatment. Both deep infiltrating endometriosis (DIE) and ovarian endometrioma (OV) are characterized by dense surrounding fibrotic tissue. However, …

Published: Oct. 24, 2025, midnight
HMGB-1 Increases Proinflammatory Reaction via TLR4 in Human Granulosa Cells of Endometriosis.

Background/Objectives: Oxidative stress is a critical factor in the development and progression of endometriosis. Granulosa cells, which reside near oocytes in follicles, exhibit steroidogenic activity, and, consequently, influence oocyte quality. …

Published: Oct. 24, 2025, midnight
Targeting Steroid Receptor Coactivators for the Treatment of Benign Female Reproductive Disorders.

Steroid receptor coactivators (SRCs) are master regulators of nuclear receptor signaling and play essential roles in female reproductive physiology. By integrating steroid hormone signaling with growth factors and metabolic pathways, …

Published: Oct. 23, 2025, midnight
ASCO Reading Room | Here's How the Treatment Landscape for Gynecologic Cancers Is About to Change - MedPage Today

ASCO Reading Room | Here's How the Treatment Landscape for Gynecologic Cancers Is About to Change MedPage Today

Published: Oct. 22, 2025, 2:54 p.m.
French medical technology company EDAP secures €36 million credit facility from EIB to advance prostate cancer and endometriosis non-invasive treatment - The European Sting

French medical technology company EDAP secures €36 million credit facility from EIB to advance prostate cancer and endometriosis non-invasive treatment The European Sting

Published: Oct. 22, 2025, 2 p.m.
Cyclana Bio raises £5m to advance endometriosis treatment - Med-Tech Insights

Cyclana Bio raises £5m to advance endometriosis treatment Med-Tech Insights

Published: Oct. 22, 2025, 1:30 p.m.
‘It’s not just cramps’: Women forced to seek endometriosis treatment privately amid long NHS waiting times - Suffolk News

‘It’s not just cramps’: Women forced to seek endometriosis treatment privately amid long NHS waiting times Suffolk News

Published: Oct. 22, 2025, 4 a.m.
Honokiol inhibits cell migration and invasion by blocking EMT via Snail/Slug axis in endometriosis.

Endometriosis, a common gynecological disease, leads to dysmenorrhea and infertility. EMT process was closely related to the pathology of endometriosis. More therapies were required to be explored for endometriosis management. …

Published: Oct. 22, 2025, midnight
Digital Health Technologies in the Treatment of Chronic Pelvic Pain Syndromes: A Systematic Review of Randomized Clinical Trials.

Objective: To comprehensively examine the qualitative results of current studies reporting the efficacy of digital health (DH) technologies in the treatment of chronic pelvic pain syndromes (CPPS) and to describe …

Published: Oct. 22, 2025, midnight
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