Dual Targeting of Orphan Nuclear Receptors NR4A1 and NR4A2 for Non-Hormonal Endometriosis Therapy.
Previous studies show that orphan nuclear receptor 4A1 (NR4A1) regulated endometriotic cell growth, survival, estrogen receptor β (ERβ), mTOR signaling and fibrosis. NR4A2 is also expressed in epithelial and stromal …
Oxidative DNA damage may promote the development of endometriosis by activating telomerase and extending telomere length: a meta-analysis.
To investigate the associations between oxidative DNA damage biomarkers [levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG), telomere length (TL), human telomerase reverse transcriptase (hTERT), telomerase activity (TA) and polymorphisms of human 8-oxoguanine glycosylase …