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Prospective evaluation of plasma proteins in relation to surgical endometriosis diagnosis in the Nurses' Health Study II.

Endometriosis is a chronic inflammatory condition characterised by pain and infertility. We conducted a prospective study to elucidate the pathophysiological mechanisms underlying endometriosis development.

Published: April 10, 2025, midnight
Current Insights into Endometriosis: Hormonal Management, Clinical Outcomes, and Opportunities for Progress.

Endometriosis, a prevalent women's health condition, is associated with persistent pelvic pain and infertility. Despite ongoing research, its precise disease mechanism remains elusive, impeding the discovery of a definitive cure. …

Published: April 8, 2025, midnight
The role of gut and vaginal microbiomes in reproductive health: Implications for PCOS, endometriosis, pre-eclampsia, and beyond.

The interplay between the gut microbiome and reproductive health has gained increasing attention in recent years. Emerging research suggests that imbalances in the gut microbiome may impact reproductive function through …

Published: April 7, 2025, midnight
Influence of endometrial nerve fibers and hormones on pain in women with endometriosis.

The mechanisms behind endometriosis-related pain are not yet fully understood. To determine if there is a difference in the density of endometrial nerve fibers between women with endometriosis and healthy …

Published: April 1, 2025, midnight
The Effects of Endometriosis on Oocyte and Embryo Quality.

Endometriosis is a complex and multifaceted gynecological disorder characterized by the abnormal growth and presence of endometrial-like tissue outside the confines of the uterine cavity. It can lead to a …

Published: March 28, 2025, midnight
Ferroptosis in Endometriosis: Traditional Chinese Medicine Interventions and Mechanistic Insights.

Endometriosis (EMS) is a chronic, estrogen-dependent inflammatory disease affecting 5-10% of women of reproductive age, characterized by the growth of endometrial tissue on the outside of the uterus. The dysregulation …

Published: March 27, 2025, midnight
Endometriosis Severity and Risk of Preeclampsia: A Combined Mendelian Randomization and Observational Study.

Endometriosis has been hypothesized to increase the risk of preeclampsia (PE) and eclampsia, although the exact mechanism of this relationship is not clear. This study aimed to further explore the …

Published: March 27, 2025, midnight
A novel senotherapeutic strategy with azithromycin for preventing endometriosis progression.

Endometriosis is an estrogen-dependent chronic inflammatory disease, however the mechanisms underlying inflammation remain unclear. Non-hormonal drugs that can prevent endometriosis progression and resolve endometriotic infertility are urgently required. We thus …

Published: March 26, 2025, midnight
A new perspective on endometriosis: Integrating eQTL mendelian randomization with transcriptomics and single-cell data analyses.

Endometriosis is caused by the migration of endometrial cells to locations outside the uterine lining. Despite the increasing prevalence of endometriosis, there has been limited research on genetic effects, and …

Published: March 26, 2025, midnight
The Role of Exosomal miRNAs in Female Infertility: Therapeutic Potential and Mechanisms of Action.

Reproductive disorders, including preeclampsia (PE), endometriosis, premature ovarian failure (POF), and polycystic ovary syndrome (PCOS), present substantial challenges to women's reproductive health. Exosomes (EXOs) are cell-derived vesicles containing molecules that …

Published: March 24, 2025, midnight
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