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Endometrial dysfunction in embryo implantation: from molecular mechanisms to clinical management.

Endometrial dysfunction represents a central pathological factor underlying recurrent implantation failure and infertility. This review provides a comprehensive synthesis of the physiological basis of endometrial function, the pathological factors compromising …

Published: June 18, 2026, midnight
Case Report: Malignant transformation of deep infiltrating endometriosis: a report of two cases and literature review.

Deep infiltrating endometriosis (DIE) is a severe form of endometriosis that rarely undergoes malignant transformation, and when it does, diagnosis is often difficult. Here, we report two cases of long-standing …

Published: June 18, 2026, midnight
Placenta Accreta Spectrum Risk in Endometriosis: A Retrospective Cohort Study with ART Subanalysis.

Background/Objectives: This study assessed whether endometriosis is associated with an increased risk of placenta accreta spectrum (PAS) disorders and investigated if assisted reproductive technology (ART) further increases the risk in …

Published: June 17, 2026, midnight
Mesenchymal Stem Cells Therapy for Intrauterine Adhesions and Endometriosis: Potential, Mechanisms, and Future Directions.

Intrauterine adhesions (IUA) and endometriosis are debilitating gynecological disorders that impair endometrial function and fertility. IUA, typically caused by iatrogenic trauma to the basal endometrium, leads to fibrosis and infertility, …

Published: June 14, 2026, midnight
Diagnostic Accuracy of Hysterosalpingography Compared With Laparoscopy in Assessing Tubal Patency Among Subfertile Women: A Retrospective Cohort Study.

Background Fallopian tube pathology accounts for approximately one-third of female factor subfertility. The National Institute for Health and Care Excellence (NICE) Fertility Guidelines (CG156) recommend hysterosalpingography (HSG) as the first-line …

Published: June 13, 2026, midnight
Emerging Pathways to Non-Invasive Diagnosis in Endometriosis: Integrating Machine Learning, Deep Learning and Multi-Omics Biomarkers.

Endometriosis is a chronic, debilitating condition affecting approximately 10-15% of reproductive-aged women and it is often associated with significant diagnostic delays due to its heterogeneity and unreliable non-invasive tests. Artificial …

Published: June 12, 2026, midnight
Epidemiology, Risk Factors, Diagnosis, and Comorbidities of Endometriosis: An Umbrella Review.

Background: Endometriosis is a chronic estrogen-dependent inflammatory disease estimated to affect up to 190 million women of reproductive age worldwide based on clinical and population-based estimates, although only 22.3 million …

Published: June 12, 2026, midnight
The role of IL-33/ST2 signaling in female reproductive diseases.

Female reproductive tissues repeatedly undergo controlled inflammation, immune adaptation, and tissue repair. Interleukin-33 (IL-33) and its receptor suppression of tumorigenicity 2 (ST2) sit at the center of these processes, but …

Published: June 12, 2026, midnight
p16 Beyond Senescence: Cancer Biology Lessons Applied to Endometriosis.

Endometriosis is an estrogen-dependent disease characterized by chronic inflammation and fibrosis and is a major cause of pelvic pain and infertility. Recent studies have reported dysregulated expression of p16INK4a, a …

Published: June 11, 2026, midnight
ENDO-GYM: A holistic approach with pelvic floor physiotherapy and Yoga for endometriosis pain relief.

To retrospectively evaluate the impact of ENDO-GYM Program, which combined Yoga practice and pelvic floor physiotherapy (PFP), on women with ultrasound and/or post-operative histological diagnosis of endometriosis pain resistant to …

Published: June 11, 2026, midnight
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