Latest Articles

Age of diagnosis with endometriosis and potential predicting factors: A single-center cross-sectional study.

To evaluate the behavioral and clinical characteristics of endometriosis patients at the largest tertiary healthcare center in Lebanon and to analyze the effect of endometriosis symptoms, age of menarche, sexual …

In vitro exploration of the therapeutic potential of mesenchymal stem cell conditioned medium in endometriosis treatment by targeting apoptosis and cellular migration.

Endometriosis, a common gynecological disorder involving ectopic endometrial tissue, leads to infertility and chronic pain. Dysregulated apoptosis and abnormal cell migration are key pathological features. Given current treatment limitations, novel …

Pathogenesis of Adenomyosis: An Integrated Review of Cellular Origins, Molecular Mechanisms, and Intersecting Diseases.

Adenomyosis is a prevalent disorder of the archimetra, historically conflated with endometriosis but possessing a unique pathobiological trajectory. This review synthesises current molecular evidence to propose a unified mechanistic framework …

Novel insights into the role of Annexin A2 signaling pathway in female reproductive system diseases: from mechanisms to advanced therapies.

Annexin A2 (ANXA2) is a calcium-dependent protein with high affinity for phospholipids, and its multifunctional nature has drawn increasing attention in the onset and progression of various disorders of the …

Novel Insights into the Pathogenic Role of CSF1R in Endometriosis.

Endometriosis (EM) is a prevalent gynecological disorder linked to pelvic pain, menstrual disturbances, and infertility. Despite its clinical burden, the molecular mechanisms underlying EM remain elusive, necessitating the discovery of …

A retrospective analysis of chronic endometritis and antibiotic therapy in patients with endometriosis.

A novel magnetic resonance imaging index to evaluate ovarian reserve in endometrioma patients: the ovary to endometrioma volume index.

Ovarian endometrioma is a common form of endometriosis associated with chronic pelvic pain, infertility, and diminished ovarian reserve. Although anti-Müllerian hormone (AMH) is widely used to evaluate ovarian reserve, it …

Endometrial NCOR1 deficiency contributes to implantation failure in endometriosis-associated infertility.

Endometriosis-associated infertility is a complex condition in which the presence of endometrial-like tissue disrupts implantation and early pregnancy. Epigenetic regulators are critical for implantation and decidualization, yet their contribution to …

Magnetic Resonance Imaging as a Non-Surgical Predictor of Endometriosis Fertility Index Surgical Factors.

Endometriosis affects 6%-10% of women of reproductive age and is associated with chronic pelvic pain, infertility, and impaired quality of life. The endometriosis fertility index (EFI) predicts spontaneous pregnancy postoperatively, …

Endometriosis treatment pathways in the largest private health insurance in Brazil: A real-world data study.

Endometriosis is a prevalent chronic gynecological condition affecting women of reproductive age, characterized by ectopic endometrial-like tissue growth. Despite its significant impact on quality of life, fertility, and healthcare utilization, …