To evaluate the effects of letrozole alone and in combination with a gonadotropin-releasing hormone agonist on inflammatory cytokines, folliculogenesis, and hormonal profiles in a rat model of surgically induced peritoneal …
Background: Endometriosis is a complex condition that impairs women's quality of life and reproductive potential. Its diagnosis remains significant challenge for clinicians. The aim of the study was to investigate …
A murine model of endometriosis was employed to evaluate the pharmacological efficacy of therapeutic compounds. Endometriosis was modeled by autotransplantation of uterine horn fragments onto the intestinal mesentery in three …
Endometriosis is a prevalent gynecological disorder associated with chronic low-grade inflammation, yet diagnosis is often delayed because symptoms are non-specific and definitive confirmation typically relies on invasive procedures. Composite indices …
Trigeminal nerve injury can lead to chronic and difficult-to-treat orofacial neuropathic pain. Here, we uncover a key role for the cation channel TRPM3 in the chronic constriction injury of the …
Endometriosis (EM) is a condition that impacts roughly 10% of women within the reproductive age demographic on a global scale. Due to the limitations of conventional diagnostic techniques for endometriosis, …
Endometriosis affects 11% of women of reproductive age. Diagnosis is often delayed by 6-8 years due to nonspecific symptoms and lack of early detection tools. This study aimed to develop …
How does the traditional Chinese compound Bushen Xiaozheng Decoction (BSXZD) affect the immunosuppressive microenvironment in rat endometriosis models?
This study evaluates the synergistic therapeutic effect of metformin (MET) combined with medroxyprogesterone acetate (MPA) on endometriosis (EM) and investigates the involvement of the steroid receptor coactivator-1 (SRC-1) and mitogen-inducible …
Endometriosis is a common gynecological disease associated with pelvic pain and infertility. Despite several existing theories, the etiology and molecular mechanisms of endometriosis remain to be investigated. Here we report …