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Tetramethylpyrazine Confers Protection Against Oxidative Stress and NLRP3-Dependent Pyroptosis in Rats with Endometriosis.

Tetramethylpyrazine (TMP) has been confirmed to suppress inflammation in endometriosis (EMs). Herein, this study investigated whether and how TMP affected NLRP3 inflammasomes and oxidative stress in EMs. After establishment of …

Published: Feb. 18, 2025, midnight
Reproductive tract microbiome dysbiosis associated with gynecological diseases.

Female health and the microbiota of the reproductive tract are closely associated. The research scope on reproductive tract microbiota extends from the vaginal to the upper reproductive tract and from …

Published: Feb. 18, 2025, midnight
The integral roles of the TGFβ signaling pathway in uterine function and disease.

The uterus is a complex organ that requires precise signaling networks to mediate functions necessary for homeostasis and reproductive processes. The transforming growth factor β (TGFβ) superfamily regulates integral signaling …

Published: Feb. 14, 2025, midnight
Endometriosis and adenomyosis research priorities in India and Sri Lanka: a call for regional collaboration.

Endometriosis and adenomyosis are major gynaecological conditions affecting women of reproductive age-group, particularly in low- and middle-income countries. This Health Policy outlined research priorities for India and Sri Lanka, derived …

Published: Feb. 14, 2025, midnight
Curcumol inhibits endometrial cell invasion through the NF-κB pathway in rats with endometriosis.

Curcumol (Cur) has been found to be useful in improving Endometriosis (EMS), however its mechanism of action is still not completely understood. Based on this, the current study was carried …

Published: Feb. 12, 2025, 12:13 a.m.
Spectrochemical differentiation in endometriosis based on infrared spectroscopy advanced data fusion and multivariate analysis.

Endometriosis is a common benign gynecological condition characterized by the growth of endometrial gland and stroma located outside the uterine cavity, which the current approaches for its detection are invasive …

Published: Feb. 11, 2025, midnight
MEIS1-mediated Apoptosis via TNFR1 in Endometriosis.

Abnormal apoptosis both maintains endometrial cell growth and induces endometrial pathogenesis. The etiology of endometriosis is unclear and no treatment is curative. Therefore, the aim herein was to identify genes …

Published: Feb. 11, 2025, midnight
The impact of MTHFR and VDR polymorphisms on endometriosis susceptibility: Insights from a systematic review and meta-analysis.

The VDR and MTHFR polymorphisms have been linked to many gynecological and obstetrical diseases. However, there is still a pressing need for a systematic review and meta-analysis to synthesize the …

Published: Feb. 6, 2025, midnight
Unraveling the role of lncRNA in Endometriosis-Associated immune system Dysregulation: Exploring the intricate immunological changes and disrupted signaling pathways.

A chronic illness known as endometriosis impacts women who are of reproductive maturity. It may be a factor in fertility problems, breast or ovarian cancer, asthma, cardiovascular illness, or pelvic …

Published: Feb. 5, 2025, midnight
Transforming the #Enzian classification into a four-stage system: A feasibility study by comparison with the 2021 AAGL endometriosis classification.

To develop a translation model of the #Enzian classification into a 4-stage system and to evaluate its performance in a retrospective endometriosis cohort.

Published: Feb. 5, 2025, midnight
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