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Revisiting endometriosis management: Polyphenols as alternative therapeutic candidates.

Endometriosis (EM) is a common gynecological disorder imposing a considerable burden on the quality of life of women through chronic pain, infertility, and other clinical manifestations. The effectiveness of management …

Published: June 24, 2026, midnight
The effect of ovarian stimulation protocol on follicular asynchrony during in vitro fertilization - A retrospective cohort study.

To examine the effect of controlled ovarian stimulation (COS) protocol on follicular synchrony in a subsequent in vitro fertilization (IVF) cycle in patients whose previous cycle was canceled due to …

Published: June 24, 2026, midnight
Does surgeon expertise influence long-term outcomes in ovarian endometrioma rupture cases?

Spontaneous ovarian endometrioma rupture typically presents with acute abdominal pain, a condition often complicated by tissue edema and pelvic adhesions that increase surgical difficulty. This study aims to evaluate the …

Published: June 24, 2026, midnight
Peritoneal Incretin Deficiency and Tirzepatide as a Multi-Axis Adjuvant Hypothesis in Treatment-Refractory Endometriosis: A Mechanistic Framework Linking Metabolism, Immunity, Fibrosis, and Nociception.

Endometriosis is increasingly recognized as a chronic systemic disorder extending beyond the classical estrogen-dependent paradigm, integrating metabolic, immune, fibrotic, and nociceptive pathways that sustain lesion persistence and refractory pelvic pain. …

Published: June 24, 2026, midnight
The Follicular Immune Checkpoint: PD-1/PD-L1 and Immune Tolerance in Oocyte Competence and IVF Failure.

Oocyte formation occurs successfully within a meticulously controlled follicular environment characterized by well-documented endocrine, metabolic, and paracrine signals. Yet, the immunological landscape of the follicle and its role in influencing …

Published: June 24, 2026, midnight
Interactions Between Neurotrophins and Ovarian Steroids in Endometriosis and Their Implications for Neuroangiogenesis: A Narrative Review.

Endometriosis is a long-term gynecological condition marked by the growth of endometrial-like tissue outside the uterus, which undergoes proliferation, bleeding, and regeneration. This disease is associated with disrupted steroid hormone …

Published: June 24, 2026, midnight
Conventional laparoscopic segmental bowel resection with mini-laparotomy specimen extraction compared with Natural Orifice Specimen Extraction (NOSE) procedures in patients with colorectal endometriosis.

In patients with colorectal endometriosis the optimal surgical approach for excising disease remains unknown.

Published: June 23, 2026, midnight
Hyaluronic Acid Enriched Medium for Embryo Transfer: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis of randomized controlled trials (RCTs) evaluated whether the use of hyaluronic acid (HA)-enriched medium for embryo transfer (ET) improves live birth rates in in-vitro fertilization …

Published: June 23, 2026, midnight
Postoperative and long-term outcomes of nerve-sparing segmental rectal resection and complete nodular resection of rectal endometriosis.

Rectal endometriosis is a severe form of deep endometriosis affecting up to 12% of patients, causing significant pain and bowel dysfunction. The optimal surgical approach can be individually tailored based …

Published: June 23, 2026, midnight
Fertility-sparing strategy in a rare case of uterine adenosarcoma and consecutive spontaneous pregnancy and livebirth.

We present the rare case of a 29-year-old patient with uterine adenosarcoma who received fertility-sparing treatment, subsequently conceived spontaneously, and gave birth to a healthy infant.

Published: June 23, 2026, midnight
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