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GHRH and reproductive systems: Mechanisms, functions, and clinical implications.

Growth hormone-releasing hormone (GHRH) has classically been considered a regulatory neuropeptide of the hypothalamic-pituitary system, which mediates its anabolic effects through hepatic GH/IGF-I axis. However, during the last decades it …

Published: Nov. 29, 2024, midnight
Female reproductive disease, endometriosis: From inflammation to infertility.

Despite the fact that endometriosis is a common gynecological disease that occurs in 10% of women of reproductive age, the pathogenesis and treatment strategy are not clear to date. Endometriosis …

Published: Nov. 29, 2024, midnight
Unraveling the complexity of follicular fluid: insights into its composition, function, and clinical implications.

Follicular fluid (FF) plays a vital role in the bidirectional communication between oocytes and granulosa cells (GCs), regulating and promoting oocyte growth and development. This fluid constitutes a complex microenvironment, …

Published: Nov. 26, 2024, midnight
A Case Report on Endometriosis-Associated Intestinal Tumour Following Hysterectomy: Diagnostic Challenges and Implications for Hormone Replacement Therapy (HRT) Guidelines - Cureus

A Case Report on Endometriosis-Associated Intestinal Tumour Following Hysterectomy: Diagnostic Challenges and Implications for Hormone Replacement Therapy (HRT) Guidelines Cureus

Published: Nov. 23, 2024, 3:36 p.m.
A Case of Early-Stage Lower Uterine Segment Carcinoma With Hysteroscopic Observation of Visual Changes Induced by a Gonadotropin-Releasing Hormone (GnRH) Antagonist - Cureus

A Case of Early-Stage Lower Uterine Segment Carcinoma With Hysteroscopic Observation of Visual Changes Induced by a Gonadotropin-Releasing Hormone (GnRH) Antagonist Cureus

Published: Nov. 23, 2024, 11:41 a.m.
A Case Report on Endometriosis-Associated Intestinal Tumour Following Hysterectomy: Diagnostic Challenges and Implications for Hormone Replacement Therapy (HRT) Guidelines.

Endometriosis is a complex condition that is often underdiagnosed, leaving rare but serious risks such as malignant transformation overlooked in many cases. Malignant transformation, especially in extra-gynaecological sites, poses significant …

Published: Nov. 23, 2024, midnight
Recurrence rates and associated risk factors after conservative surgery for adenomyosis: a retrospective study.

Conservative surgery for adenomyosis has been shown to be effective. However, risk factors for postoperative recurrence have yet to be clarified. In this study, we aimed to determine the recurrence …

Published: Nov. 22, 2024, midnight
Efficacy and Safety of Oral Gonadotropin-Releasing Hormone Antagonist, Relugolix, in Endometriosis: A Meta-Analysis of Randomized Clinical Trials.

Published: Nov. 20, 2024, midnight
A Cost-Effectiveness Analysis of Gonadotropins Used for Ovarian Stimulation during Assisted Reproductive Technology Based on Data from the French Nationwide Claims Database (SNDS).

Various gonadotropins are used for ovarian stimulation (OS). This study investigated the cost-effectiveness of different gonadotropins based on real-world data from the French National Health Database (SNDS) over a 7-year …

Published: Nov. 19, 2024, midnight
Comparative Analysis of Medical Interventions to Alleviate Endometriosis-Related Pain: A Systematic Review and Network Meta-Analysis.

Background/Objectives: Endometriosis is a chronic condition that affects 6-10% of women of reproductive age, with pain and infertility being its primary symptoms. The most common aspects of pain are overall …

Published: Nov. 18, 2024, midnight
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