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ATOPE study protocol: a randomised controlled trial comparing cystectomy and plasma vapourisation in endometriomas under 6 cm, with an observational arm for sclerotherapy in larger cysts.

The Ablative Technique Options for Preserving fertility in Endometrioma study is a prospective, monocentric clinical study that combines a randomised controlled trial comparing cystectomy and plasma vapourisation for endometriomas measuring …

Published: April 28, 2026, midnight
The impact of endometriosis on long-term neurologic morbidity of the offspring: a population-based analysis.

Endometriosis, a chronic inflammatory disease, has been associated with adverse pregnancy and perinatal outcomes, which in turn have been linked to long-term neurological morbidity in the offspring. This study aimed …

Published: April 25, 2026, midnight
Reproductive Pathways Across the Lifespan and Their Mental Health Impacts.

Reproductive health unfolds across the lifespan, and individuals may move through diverse pathways - including infertility, chronic gynecologic conditions such as endometriosis, pregnancy complications, assisted reproduction or gestational carriage. These …

Published: April 22, 2026, midnight
Medical and Surgical Management of Endometriosis: A Narrative Review of Clinical Outcomes.

Endometriosis is a chronic, estrogen-dependent, and heterogeneous gynecologic disorder associated with persistent pain, infertility, and substantial impairment in quality of life (QoL), necessitating individualized and evidence-based management. This narrative review …

Published: April 16, 2026, midnight
Novel insights into the role of Annexin A2 signaling pathway in female reproductive system diseases: from mechanisms to advanced therapies.

Annexin A2 (ANXA2) is a calcium-dependent protein with high affinity for phospholipids, and its multifunctional nature has drawn increasing attention in the onset and progression of various disorders of the …

Published: April 14, 2026, midnight
Managing the aftermath: complications and outcome after colorectal resection for deep infiltrating endometriosis-insights from a certified surgical endoscopy center.

Deep infiltrating endometriosis (DIE) often affects the bowel and may necessitate colorectal resection. While protective ileostomy can reduce complications, it carries relevant morbidity. This study evaluates endoscopic complication management and …

Published: April 9, 2026, midnight
Is colorectal resection necessary to improve pain and fertility outcomes in patients with deep endometriosis?

Bowel endometriosis is often considered an indication for extensive surgical management, including colorectal resection, in women undergoing surgery for concomitant endometriosis at other sites. However, several contemporary studies show little …

Published: April 8, 2026, midnight
Unusual presentation of endometriosis as a large tubo-ovarian abscess posing a diagnostic challenge.

Tubo-ovarian abscess (TOA) is a severe complication of pelvic inflammatory disease (PID), but it can also occur in women without prior PID or sexually transmitted infections. Recent studies suggest that …

Published: April 7, 2026, midnight
Clinical Efficacy of Dienogest for Symptomatic Adenomyosis.

Background: This study was conducted to assess whether medical treatment with dienogest (DNG) is effective in women with symptomatic adenomyosis. Methods: This single-center, retrospective study included patients with symptomatic adenomyosis …

Published: April 6, 2026, midnight
Major postoperative complications after endometriosis surgery: incidence and outcomes from a multicenter French cohort.

Surgery is a therapeutic option for patients with deep endometriosis presenting with infertility and/or pain refractory to medical treatment. Major postoperative complications may impair quality of life and delay the …

Published: April 3, 2026, midnight
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