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Functions of Estrogen and Estrogen-Related Receptors in Diseases of the Female Reproductive System.

Diseases of the female reproductive system are prevalent. These conditions often have a high proportion of asymptomatic patients and prolonged treatment durations. Estrogen, a crucial steroid hormone, plays a central …

Published: Oct. 10, 2025, midnight
NLRP3 Inflammasome in Gynecologic Inflammatory Diseases: Mechanisms, Pathophysiology, and Therapeutic Strategies.

The NOD-like receptor family containing pyridine domain 3 (NLRP3) inflammasome serves as a pivotal mediator of innate immune responses and a central driver of inflammatory processes. Upon detection of pathogenic …

Published: Oct. 10, 2025, midnight
Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System.

The ascent of novel alternative methods (NAMs) in drug development spotlights the dual needs for improved biological fidelity to in vivo along with reproducibility, especially in regulatory applications. The need …

Published: Oct. 6, 2025, midnight
Weight-loss drugs now linked to cancer protection in women, major new study reveals - WCCS AM1160 & 101.1FM

Weight-loss drugs now linked to cancer protection in women, major new study reveals WCCS AM1160 & 101.1FM

Published: Sept. 29, 2025, 11:37 a.m.
Weight-loss drugs now linked to cancer protection in women, major new study reveals - Fox News

Weight-loss drugs now linked to cancer protection in women, major new study reveals Fox News

Published: Sept. 29, 2025, 11 a.m.
Migraine molecules may drive endometriosis pain. Existing drugs might help. - MSN

Migraine molecules may drive endometriosis pain. Existing drugs might help. MSN

Published: Sept. 29, 2025, 4:26 a.m.
Endometriosis Pipeline Drugs Report 2025: DelveInsight's - openPR.com

Endometriosis Pipeline Drugs Report 2025: DelveInsight's openPR.com

Published: Sept. 19, 2025, 2:04 a.m.
Using systems biology and drug repositioning approaches to discover FDA-approved drugs candidates for endometriosis treatment.

Endometriosis is characterized by the presence of endometrial tissue outside the uterine cavity. The administration of drugs designated for this condition has significant adverse effects, such as signs of estrogen …

Published: Sept. 12, 2025, midnight
Integrative analysis reveals ferroptosis-related genes with RRM2 as a key driver in endometriosis.

Endometriosis is an estrogen-dependent disorder with unclear molecular mechanisms. Ferroptosis, a regulated iron-dependent cell death, may play a key role, yet the specific genes involved remain underexplored.

Published: Sept. 10, 2025, midnight
Erastin-induced multi-pathway cell death in endometriosis: a mechanistic and translational narrative review.

This narrative review examines the therapeutic potential of Erastin and its derivatives for endometriosis (EMS) by integrating mechanistic, preclinical, and translational perspectives. We conducted a focused review of literature from …

Published: Sept. 10, 2025, midnight
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