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Glycolytic Reprogramming in Endometriosis: Biological Basis and Emerging Targets for Disease-Modifying Therapy.

Endometriosis is a chronic gynecological disease affecting approximately 10% of women of reproductive age and up to 40% of women with infertility, with a significant impact on quality of life …

Published: July 23, 2026, midnight
Reply to "Reassessing the Proposed Creatine-PrP Axis in Endometriosis: Methodological and Mechanistic Considerations".

This Correspondence is a formal response to the Comment by Dr. Machado regarding our publication "Creatine Promotes Endometriosis by Inducing Ferroptosis Resistance via Suppression of PrP." We address several conceptual …

Published: July 20, 2026, midnight
Somatic Cancer Driver Mutation Analysis in Endometriosis with Tumor-like Presentations: A Case Series Study.

Background/Objectives: Endometriosis manifests as ectopic endometrial tissue outside the uterine cavity. This lesion can sometimes appear at unusual anatomical sites or within the intestinal tract, growing and mimicking cancer. Such …

Published: July 20, 2026, midnight
A systematic approach to standardizing the visual appearance of endometriotic lesions for artificial intelligence recognition.

Numerous studies have shown that the diagnostic performance and reproducibility of visual recognition of endometriosis during laparoscopy are poor. The use of artificial intelligence (AI) seems relevant for exhaustive lesion …

Published: July 11, 2026, midnight
Comprehensive transcript and protein profiling reveals ERα rather than ERβ as the predominant estrogen receptor in human endometriotic lesions.

Endometriosis (EMS) is a chronic estrogen-dependent inflammatory disease. Although several studies have suggested a key role for estrogen receptor ERβ in EMS lesion development, its detection has been challenged by …

Published: July 11, 2026, midnight
Reproductive Outcomes Following Minimally Invasive Surgery for Deep Endometriosis: A Cohort Study.

Objective: To evaluate reproductive outcomes following fertility-sparing surgery for deep endometriosis (DE), specifically assessing the impact of bowel resection on spontaneous conception rates and the predictive value of the Endometriosis …

Published: July 9, 2026, midnight
Functional Analysis of the Histidine N-Methyltransferase SETD3 in Endometriosis.

Endometriosis is a disease associated with pain symptoms and reduced fertility, characterized by the presence of endometrial tissue outside the uterus. SETD3 is an actin-specific histidine N-methyltransferase that regulates actin …

Published: July 7, 2026, midnight
PGRMC1 suppression enhances progesterone responsiveness in stromal cells of ovarian endometrioma.

Progesterone resistance in endometriosis reduces the efficacy of progestin. The non-classical progesterone receptor, progesterone receptor membrane component 1 (PGRMC1) may regulate progesterone signaling in the normal endometrium, but its expression …

Published: July 6, 2026, midnight
The Association Between Endometriosis and an Increased Risk of Epithelial Ovarian Cancer and Cardiovascular Disease: Perspective on a Patient-Centered Approach to Endometriosis, a Heterogeneous Disease.

A growing body of literature has revealed that patients with endometriosis are at an increased risk for epithelial ovarian cancer (EOC) and cardiovascular disease (CVD). Endometriosis is a heterogeneous disease …

Published: July 6, 2026, midnight
Steroidal alkaloids as multi-target therapeutics for the treatment of endometriosis.

Endometriosis is a chronic inflammatory disease characterised by ectopic endometrial tissue, progressive fibrosis and chronic pain, with a pathogenesis that goes beyond oestrogen dependence. The central question this review seeks …

Published: July 4, 2026, midnight
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