Endometriosis is a prevalent gynecologic disorder that significantly impacts women's health. However, its underlying pathogenesis remains unknown. This study aimed to ascertain causal associations between plasma protein levels and endometriosis …
Endometriosis defined by the growth of endometrial tissues outside the uterus, affects women of reproductive age. A critical process in endometriosis progression, angiogenesis involves endothelial cell migration, proliferation and tube …
Elagolix and Myfembree are gonadotropin-releasing hormone (GnRH)-pathway therapies used for endometriosis, but their post-marketing safety reporting patterns remain incompletely characterized. Because spontaneous reporting databases are susceptible to reporting bias and …
Mycotoxins are widespread food contaminants, and urinary biomarkers reflect recent dietary exposure. Although mycotoxins have been implicated in reproductive toxicity, their impact on human oocyte and embryo development remains poorly …
Infertility currently affects nearly one in six couples, representing more than 3.3 million people in France. Infertility now occurs in an unprecedented demographic context, marked by a rapid decline in fertility: …
Endometriosis is associated with increased cardiovascular disease (CVD) risk, yet the cellular basis for this relationship remains unclear. We examined whether peritoneal fluid (PF) from women with endometriosis alters cardiomyocyte …
This preliminary study sought to provide initial insights into lead concentrations within the follicular fluid of infertile patients with and without endometriosis, tentatively observing any potential links between lead presence …
Endometriosis and adenomyosis are estrogen-dependent inflammatory conditions frequently associated with impaired fertility. Although progesterone resistance at the tissue level is well documented, it remains unclear whether these conditions are associated …
Neonatal uterine bleeding (NUB) has been hypothesized as a relatively common early-life event potentially linked to the later development of endometriosis through retrograde menstruation. However, its true prevalence and biological …
Phthalate esters (PAEs) and organophosphate esters (OPEs) are pervasive 20 environmental pollutants with endocrine-disrupting properties. Despite growing 21 evidence linking PAE/OPE exposure to female reproductive disorders, the 22 diseasespecific molecular …