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Targeting inflammation in endometriosis: emerging therapeutic options.

Endometriosis is a chronic, estrogen-dependent inflammatory disease affecting up to 10% of reproductive-aged women. Current therapies are predominantly hormone-based and offer symptomatic relief without correcting the immune dysregulation and inflammation …

Published: Dec. 24, 2025, midnight
Effectiveness of an anti-inflammatory diet before in vitro fertilisation in women with endometriosis: protocol for a randomised controlled trial.

Endometriosis is a common, benign, chronic inflammatory disease with multiple consequences, from chronic pain to systemic comorbidities and poor quality of life. As it usually affects people of reproductive age, …

Published: Dec. 23, 2025, midnight
Endometriosis as an immune-mediated disease: pathogenetic mechanisms and therapeutic strategies.

Endometriosis, which affects approximately 10% of women of reproductive age, is a complex inflammatory disease with significant immune system disturbances caused by an inadequate immune response to retrograde menstruation and …

Published: Dec. 18, 2025, midnight
Actor, 29, diagnosed with inflammatory disease after doctors dismissed mystery pain - The Independent

Actor, 29, diagnosed with inflammatory disease after doctors dismissed mystery pain The Independent

Published: Dec. 12, 2025, 7:28 a.m.
Spinal-Cord Stimulation for Intractable, Visceral Pain Associated With Endometriosis: Positive Results of a Feasibility Study.

Endometriosis, an estrogen-dependent chronic inflammatory disease, can cause visceral pain. Owing to its chronic nature, treatment can be challenging and insufficient in reducing all symptoms despite adequate management. Spinal-cord stimulation …

Published: Dec. 3, 2025, midnight
S1P3 Receptor Mediates the Proinflammatory Effect of the Endocannabinoid 2-Arachidonoylglycerol in Endometriotic Epithelial Cells.

Endometriosis is a chronic inflammatory disease characterized by the ectopic implantation of endometrium outside the uterus associated with pelvic pain and infertility. The molecular mechanisms involved in the pathogenesis of …

Published: Nov. 27, 2025, midnight
Acute Hemoperitoneum Secondary to Chronic Hematosalpinx: A Diagnostic Challenge in the Setting of a Negative Pregnancy Test.

Acute hemoperitoneum represents a gynecological and surgical emergency with significant morbidity if diagnosis and intervention are delayed. In women of reproductive age, the etiology is most frequently ruptured ectopic pregnancy; …

Published: Nov. 20, 2025, midnight
Colo-Ovarian Fistula With a Background of Endometriosis: A Report of Three Cases.

Patients with endometriosis are at a high risk of developing pelvic inflammatory disease. This case series presents three cases of colo-ovarian fistulas associated with endometriosis, highlighting the potential for conservative …

Published: Nov. 19, 2025, midnight
Curcumol alleviates endometriosis via correcting the aberrant activation of Fas/RIPK1-mediated PANoptosis.

Endometriosis (EMs) is an estrogen-dependent chronic inflammatory disease. While apoptosis resistance (evidenced by Bcl-2 upregulation and Bax/caspase-3 downregulation) remains a hallmark of EMs, recent studies reveal a paradoxical coexistence of …

Published: Nov. 18, 2025, midnight
N6-methyladenosine regulated FZD7 inhibits ferroptosis in endometriosis via β-catenin/SLC7A11 pathway.

Endometriosis (EMS), a chronic inflammatory disease affecting approximately 10% reproductive aged women, remains etiologically unclear. This study aims to investigate the role and underlying mechanisms of frizzled class receptor 7 …

Published: Nov. 13, 2025, midnight
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