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Human Endometriotic Lesion-Derived Small Extracellular Vesicles Impair Macrophage Function in the Peritoneal Microenvironment.

Endometriosis (EM) is a chronic inflammatory disease that affects ∼10% of women during reproductive age. It is characterised by ectopic (ECT) growth of endometrial-like tissue mainly in the pelvic cavity. …

Published: Feb. 20, 2026, midnight
A Dive into the Invisible: The Vaginal and Endometrial Microbiota in Gynecologic and Obstetric Disorders: A Narrative Review.

The human microbiota is increasingly recognized as a key component of women's reproductive health. This narrative review examines the vaginal, endometrial, and gut microbiota and their roles in the pathogenesis …

Published: Feb. 17, 2026, midnight
Systemic Oxidative Stress Markers in Endometriosis: Elevated Advanced Glycation End Products and Sestrin 2 in Women with Ovarian Endometrioma.

Background/Objectives: Endometriosis is a chronic inflammatory disease characterized by ectopic endometrial tissue growth and is strongly associated with oxidative stress; however, systemic biomarkers reflecting this stress response remain limited. Advanced …

Published: Feb. 10, 2026, midnight
Gut Microbiota Alterations and Reproductive Tract Dysbiosis in Endometriosis: A Systematic Review.

Background and Objectives: Endometriosis is a chronic, estrogen-dependent inflammatory disease with multifactorial pathogenesis. Increasing evidence suggests that alterations in the gut and reproductive tract microbiota may contribute to disease development, …

Published: Feb. 10, 2026, midnight
Neutrophil extracellular traps in gynecological disease: pathogenic mechanisms and therapeutic opportunities.

Gynecologic disorders, including infections, sterile inflammatory diseases, endocrine abnormalities, and malignancies, share a common signature of dysregulated immunity within a uniquely hormone-responsive reproductive tract. Neutrophil extracellular traps (NETs) are increasingly …

Published: Feb. 5, 2026, midnight
Differential gene expression profiling of ectopic endometrium reveals key molecular pathways in endometriosis pathogenesis.

Endometriosis is a chronic, estrogen-dependent inflammatory disease characterized by the presence of endometrial-like tissue outside the uterine cavity and is associated with pain, infertility, and impaired quality of life. Although …

Published: Feb. 3, 2026, midnight
Nutrition and endometriosis: evidence, limits and clinical perspectives.

Endometriosis is a chronic estrogen-dependent inflammatory disease frequently associated with gastrointestinal symptoms, metabolic comorbidities, and impaired quality of life. Growing interest in nutrition has led to the widespread dissemination of …

Published: Jan. 31, 2026, midnight
Attenuated Cyclooxygenase-Mediated Vasodilation in Cutaneous Microvasculature with No Difference in Platelet Aggregation in Women with Endometriosis.

Endometriosis is a systemic inflammatory disease known to increase the risk of cardiovascular disease. The inducible form of cyclooxygenase (COX), COX-2, is an inflammatory enzyme upregulated in endometriosis with COX …

Published: Jan. 30, 2026, midnight
Natural products modulate programmed cell death signaling mechanism for treating endometriosis: a review.

Endometriosis (EMs) is a gynecological inflammatory disease that depends on estrogen. Its chief symptoms include dysmenorrhea, chronic pelvic pain, reduced fertility, and pelvic masses. Although various hormonal therapies and surgical …

Published: Jan. 29, 2026, midnight
Identification of a circulating immunological signature as a liquid biopsy approach for the diagnosis of endometriosis.

Endometriosis is a chronic inflammatory disease characterized by ectopic endometrial tissue growth, causing pain and infertility. Diagnosis is often delayed due to reliance on imaging and invasive methods, highlighting the …

Published: Jan. 23, 2026, midnight
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