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Hope, fertility, and the ethics of clinical discernment: a personalist supplement to ethical decision-making in gynecological practice.

This article examines gynecological decision-making in clinical contexts where interventions carry significant implications for fertility and future reproductive possibilities. Conditions such as uterine fibroids, endometriosis, and ovarian cysts are commonly …

Published: July 10, 2026, midnight
Immune escape in endometriosis: mechanisms, reprogramming strategies, and precision interventions.

Endometriosis is a prevalent estrogen-dependent inflammatory disorder that compromises women's quality of life and fertility through chronic pelvic pain, inflammation, and reproductive dysfunction. Current clinical management remains largely palliative, with …

Published: July 10, 2026, midnight
Case Report: Erythema gyratum repens associated with adenomyosis and endometriosis: an immunological twist?

A 37-year-old non-Caucasian woman presented with a 2-year history of pruritic, concentric erythematous plaques refractory to multiple topical and systemic therapies. The clinical findings were highly suggestive of erythema gyratum …

Published: July 10, 2026, midnight
Metabolic remodeling of endometriosis microenvironment: Energy stress and immune evasion.

Endometriosis (EMs) is an estrogen-dependent chronic inflammatory gynecological disease characterized by ectopic growth of endometrial tissues, leading to dysmenorrhea, pelvic pain, and infertility. Although the retrograde menstruation theory clarifies the …

Published: July 9, 2026, midnight
Are We Missing the Bladder? Reflections on Endometriosis and IC/BPS.

Endometriosis and interstitial cystitis/bladder pain syndrome (IC/BPS) frequently coexist in women with chronic pelvic pain, yet overlapping symptoms and non-standardized diagnostic pathways often delay recognition of dual pathology. We propose …

Published: July 8, 2026, midnight
Nanotechnology in reproductive medicine: from gamete engineering to precision therapeutics.

Infertility represents a significant global health burden, necessitating advanced therapeutic interventions. While Assisted Reproductive Technologies have revolutionized fertility treatment, they remain constrained by limited efficacy, off-target toxicity, and procedural complexity. …

Published: July 8, 2026, midnight
Endometriosis: Epidemiology, Risk Factors, Molecular Mechanisms, Diagnosis, and Management.

Endometriosis is a chronic estrogen-dependent gynecological disorder characterized by the ectopic growth of endometrial-like tissue outside the uterine cavity, affecting approximately 10% of women of reproductive age worldwide. It is …

Published: July 8, 2026, midnight
Predictive markers of endometriosis: a future perspective.

Endometriosis is a chronic gynecological disorder affecting up to 10% of women of reproductive age and is characterized by the presence of endometrial-like tissue outside the uterus. The condition is …

Published: July 6, 2026, midnight
Effect of Fish-Derived Lipids on Inflammation Status and Health-Related Quality of Life in Women with Endometriosis.

Background: Endometriosis is a chronic, estrogen-dependent inflammatory disorder associated with pain and immune dysregulation. Omega-3 (n-3) fatty acids and fish-derived bioactive lipids may modulate inflammation and metabolism. This study investigated …

Published: July 5, 2026, midnight
The Microbiome-Gut-Gonad Axis: How Microbial Metabolites Orchestrate Reproductive Physiology, Pathology, and Therapy.

The human microbiome, a dynamic endocrine organ, exerts profound systemic influence through the production of bioactive metabolites. While the microbiome-gut-brain axis is well-established, the direct conduit between the gut microbiota …

Published: July 4, 2026, midnight
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