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Causal effects of endometriosis on serum 25-hydroxyvitamin D: Evidence from Mendelian randomization study.

The potential bidirectional causal relationship between endometriosis and serum 25-hydroxyvitamin D has been previously investigated. Nevertheless, the results could be impacted by confounding factors and reverse causality because of the …

Published: May 13, 2026, midnight
Peritoneal Hypoxia as a Gatekeeper Between Physiologic Retrograde Menstruation and Pathologic Persistence in Endometriosis.

Several hypotheses have been proposed to explain the establishment of endometriosis, of which retrograde menstruation remains the most widely accepted mechanism of dissemination. However, the mechanisms governing selective lesion establishment …

Published: May 12, 2026, midnight
Insights from an observational matched case-control study on the association between endometriosis and benign uterine disorders in infertile patients.

The link between endometriosis and other medical conditions is gaining attention. Such insights could enhance clinical approaches to manage the disease and potentially reveal new, unrecognized mechanisms of its development. …

Published: May 9, 2026, midnight
Clear cell carcinoma arising from abdominal wall endometriosis: A case report with imaging findings and pathologic correlation.

Clear cell carcinoma arising from abdominal wall endometriosis is an exceptionally rare malignancy that typically develops at prior surgical scar sites. We report a case of a woman in her …

Published: May 9, 2026, midnight
Targeting the Wnt signaling network in endometriosis: mechanistic insights and translational opportunities.

Endometriosis is a chronic gynecological disorder defined by the growth of endometrial-like tissue outside the uterus, driven by estrogen-dependent inflammation and progressive fibrosis. According to available data, remodeling and persistent …

Published: May 8, 2026, midnight
Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System.

The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for …

Published: May 6, 2026, midnight
Targeting TLR4 Attenuates Endometriosis Progression by Suppressing NF-κB/NLRP3 Inflammasome Activation and Angiogenesis.

Endometriosis is a chronic inflammatory disorder affecting approximately 10% of reproductive-age women, yet non-hormonal therapeutic options remain limited. This study investigates the role of the TLR4/NF-κB/NLRP3 inflammasome axis in endometriosis …

Published: May 6, 2026, midnight
Interpretations of Menstrual Blood Appearance and Diagnostic Potential Among Social Media Users: Cross-Sectional Mixed Methods Social Media Listening Study.

Menstruation has long been framed primarily as a hygiene issue, with mainstream products and public messaging emphasizing concealment and disposal of menstrual blood (MB). This has contributed to a culture …

Published: May 4, 2026, midnight
The paradoxical association between endometrioma size and serum anti-Müllerian hormone levels in infertile women.

The impact of endometrioma size on ovarian reserve remains controversial. Although endometriomas are known to reduce anti-Müllerian hormone (AMH) levels, some studies suggest a paradoxical association between larger cysts and …

Published: May 4, 2026, midnight
Multi-omics Mendelian randomization identifies mitochondrial genes associated with immune microenvironment signatures in endometriosis.

Endometriosis is a complex gynaecological disorder that affects 10%-15% of reproductive-age women and is characterized by chronic inflammation, pelvic pain, and infertility. Although mitochondrial dysfunction is implicated in endometriosis pathogenesis, …

Published: May 4, 2026, midnight
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