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[Analysis and projection of the disease burden of endometriosis and polycystic ovary syndrome-related infertility among women aged 15-49 years in China and globally from 1990 to 2021].

Objective: To investigate the burden of endometriosis (EMs)-related and polycystic ovary syndrome (PCOS)-related infertility among women aged 15-49 years in China and globally, and to project trends over the next …

Published: July 1, 2026, midnight
Characterizing endometriosis and adenomyosis symptom clusters and their impact on quality of life in the All of Us Research Program.

Are there distinct symptom clusters in women with endometriosis and adenomyosis, and how do these clusters predict quality of life?

Published: July 1, 2026, midnight
Endometriosis as a chronic endothelial disorder: thromboinflammation, vascular reprogramming, and systemic cardiovascular risk.

Microvascular thromboinflammation is a pervasive yet under-recognized driver of multisystem morbidity that links focal endothelial injury to distal organ dysfunction through interacting cellular and plasmatic networks. Contemporary paradigms remain fragmented: …

Published: June 30, 2026, midnight
Chemokine CCL21 promotes the pathological progression of endometriosis by regulating inflammatory cytokine expression and activating the NF-κB signaling pathway.

Endometriosis, affecting approximately 10% of reproductive-aged women worldwide, is widely recognized as a chronic inflammatory disease. Inflammation-related genes (IRGs) play a crucial role in the occurrence and progression of various …

Published: June 29, 2026, midnight
Patient-derived organoids in gynaecological cancers: emerging tools for therapy and disease modelling.

Patient-derived organoids (PDOs) have emerged as physiologically relevant three-dimensional (3D) culture systems that closely mimic the molecular and histological features of the human endometrium and associated malignancies. Owing to their …

Published: June 27, 2026, midnight
Subtype-specific analysis of factors associated with assisted reproductive technology indication and live birth in patients with adenomyosis: a retrospective study.

The magnetic resonance imaging (MRI)-based classification of adenomyosis subtypes helps predict reproductive and obstetric outcomes; however, background factors associated with use of assisted reproductive technology (ART) and live birth within …

Published: June 26, 2026, midnight
Nociception-guided opioid administration within multimodal analgesia for laparoscopic endometriosis surgery: a randomized controlled trial.

Women with endometriosis are at increased risk of severe postoperative pain due to nociceptive sensitization. While multimodal analgesia reduces opioid use, the added value of objective nociception monitoring remains unclear. …

Published: June 22, 2026, midnight
Validation of Endometriosis Fertility Index for the Prediction of Non-Assisted Reproductive Technology (ART) Pregnancy in Women With Endometriosis-Associated Infertility: A Prospective Cohort Study.

Introduction Endometriosis is a common cause of infertility and affects reproductive outcomes through multiple mechanisms, including pelvic adhesions, altered pelvic anatomy, and inflammatory changes. The Endometriosis Fertility Index (EFI) was …

Published: June 19, 2026, midnight
The Role of Molecular Characterization in Precision Medicine in Endometriosis.

Endometriosis is a chronic condition in which tissue similar to the lining of the uterus grows in other parts of the body. It affects roughly 1 in 10 women of …

Published: June 18, 2026, midnight
Motivation to join and supportive activity within online health communities among patients with persistent pain: A survey-based examination.

Online Health Communities (OHCs) are key platforms for people seeking medical information and social support. Individuals with persistent pain often use these communities to better understand their condition, share experiences, …

Published: June 18, 2026, midnight
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